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Reference Work Entry In depth
Magnesium Deficiency, Sphingolipids, and Telomerase: Relevance to Atherogenesis, Cardiovascular Diseases, and Aging
An attempt is made, herein, to reconcile, and integrate, the various phenomena associated with magnesium deficiency and etiology of various cardiovascular disorders, including atherogenesis and systemic inflam...
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Living Reference Work Entry In depth
Magnesium Deficiency, Sphingolipids, and Telomerase: Relevance to Atherogenesis, Cardiovascular Diseases, and Aging
An attempt is made, herein, to reconcile, and integrate, the various phenomena associated with magnesium deficiency and etiology of various cardiovascular disorders, including atherogenesis and systemic inflam...
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Article
C2-ceramide attenuates phenylephrine-induced vasoconstriction and elevation in [Ca2+] i in rat aortic smooth muscle
In the present study, we examined the effects of cell-permeable C2-ceramide on contraction of aortic smooth muscle and intracellular free Ca2+ ([Ca2+] i ). C2-ceramide (10−7 to 1...
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Article
Magnesium for Migraine
Magnesium deficiency can be assessed using serum ionised magnesium level, which appears to be a much more sensitive indicator of magnesium status than total serum or intracellular levels of this ion. In vitro and...
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Chapter
Transmembrane Currents in Capillary Endothelial Cells are Modulated by External Mg2+ Ions
The capillary endothelium of the brain is involved essentially in the preservation of the blood-brain barrier and in the regulation of brain microcirculation. As a biological membrane lining the inner wall of ...
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Article
Extracellular magnesium regulates intracellular free Mg2+ in vascular smooth muscle cells
Regulatory effects of extracellular magnesium ions ([Mg2+]o) on intracellular free ionized magnesium ([Mg2+]i) were exmained in cultured vascular smooth muscle cells (VSMCs) fromrat aorta by digital imaging micro...
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Article
Unusual effects of SCN and lyotropic anions on contractility of vascular smooth muscle from female rats
Replacement of extracellular chloride ions by thiocyanate anions (SCN−) followed by washout in normal chloride-containing solution produced contractions in isolated rat aortas and portal veins of female rats foll...
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Chapter
Microcirculatory Regulation and Dysfunction
Since reticuloendothelial (RE) cells are constituents of the vascular system, they can be affected, primarily, by two agencies—microcirculatory vasomotor behavior and/or vasoactive substances in the blood or l...
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Chapter
Importance of Sex and Estrogens in Amelioration of Lethal Circulatory Stress Reactions: Relationship to Microcirculatory and Reticuloendothelial System Function
Recently, sex hormones have been shown to alter the concentration of elastin and collagen in the vascular walls of chickens (1) and rats (2,3). Administration of estrogen has also been reported to result in a ...
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Chapter
Neurohumoral Control of Blood Vessels
Renkin and Rosell (1962) reported specific sites for eNS control of arterioles and precapillary sphincters. Gootman et al. (1973) showed that all segments of precapillary microvessel and sphincter can respond to ...
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Chapter
Reticuloendothelial Function in Experimental Injury and Tolerance to Shock
Although the morphology, ultrastructure and functions of the reticuloendothelial system (RES) are becoming well documented (64, 72), most of the information is immunologically oriented. The role of the RES in ...
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Chapter
A Structure-Activity Basis for Vasotropic Peptide Therapy in Shock
Chemical analogues which enhance one or several biologic properties of important naturally occurring substances are regularly sought. Currently in this regard, there is intense interest in develo** such anal...
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Chapter
Structure-Activity Relationships of Neurohypophyseal Polypeptides on Different Types of Isolated Mammalian Blood Vessels
Up until the isolation and synthesis of vasopressin in 1953 by du Vigneaud vasopressin was given little serious thought as a useful vasoactive drug because of its well documented coronary constrictor action. I...
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Chapter
Microcirculatory Actions of Polypeptides and Their Use in the Treatment of Experimental Shock
In the normal regulation of the microcirculation it is generally accepted that the catecholamines serve as the undifferential tonic constrictor influence on the muscular mîcrovessels(1). To achieve appropriate...
