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  1. No Access

    Article

    High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1

    Bladder outlet obstruction (BOO) results in significant fibrosis in the chronic stage and elevated bladder pressure. Piezo1 is a type of mechanosensitive (MS) channel that directly responds to mechanical stimu...

    Bo-lang Deng, Dong-xu Lin, Zhi-peng Li, Kang Li, Peng-yu Wei in Current Medical Science (2024)

  2. Article

    Open Access

    Effects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis

    Non-pharmacological interventions have a myriad of available intervention options and contain multiple components. Whether specific components of non-pharmacological interventions or combinations are superior ...

    **ao-Hong Yu, **n-Ru Li, Zhi-Run Du, Yu Zhang, Yang Fei, Wen-** Tang in BMC Medicine (2024)

  3. No Access

    Article

    Effectiveness of Lianhua Qingwen Granule and **gyin Gubiao Prescription in Omicron BA.2 Infection and Hospitalization: A Real-World Study of 56,244 Cases in Shanghai, China

    To examine the effectiveness of Chinese medicine (CM) Lianhua Qingwen Granule (LHQW) and **gyin Gubiao Prescription (JYGB) in asymptomatic or mild patients with Omicron infection in the shelter hospital.

    Yu-jie Zhang, Guo-jian Liu, Han Zhang, Chen Liu in Chinese Journal of Integrative Medicine (2024)

  4. Article

    Open Access

    Electrophysiological characteristics and catheter ablation of ventricular arrhythmias arising from the superior septal left ventricle

    Electrophysiological characteristics and radiofrequency catheter ablation (RFCA) of premature ventricular contractions (PVCs) originating from the superior septal left ventricle (SSLV) have not yet been fully ...

    Qifang Liu, Ye Tian, Zhi Jiang, Longhai Tian, **g Huang in BMC Cardiovascular Disorders (2024)

  5. Article

    Open Access

    The Causal Association Between Blood Lead and Sleep Disorders: Evidence from National Health and Nutrition Examination Survey and Mendelian Randomization Analysis

    Poor sleep quality is a global public health concern. This study aimed to identify the risk factors for sleep disorders and clarify their causal effects.

    Shengnan Chen, Ming Zhang, Weisong Zhang in Journal of Epidemiology and Global Health (2024)

  6. Article

    Open Access

    Physical frailty, genetic predisposition, and incident dementia: a large prospective cohort study

    Physical frailty and genetic factors are both risk factors for increased dementia; nevertheless, the joint effect remains unclear. This study aimed to investigated the long-term relationship between physical f...

    Pei-Yang Gao, Ling-Zhi Ma, Xue-Jie Wang, Bang-Sheng Wu in Translational Psychiatry (2024)

  7. Article

    Open Access

    The potential association between metabolic disorders and pulmonary tuberculosis: a Mendelian randomization study

    Metabolic disorders (MetDs) have been demonstrated to be closely linked to numerous diseases. However, the precise association between MetDs and pulmonary tuberculosis (PTB) remains poorly understood.

    Zhi-xiang Du, Yun-yao Ren, Jia-luo Wang in European Journal of Medical Research (2024)

  8. Article

    Open Access

    Association between vitamin B2 intake and prostate-specific antigen in American men: 2003–2010 National Health and Nutrition Examination Survey

    Accumulating evidence suggests a pivotal role of vitamin B2 in the pathogenesis and progression of prostate cancer (PCa). Vitamin B2 intake has been postulated to modulate the screening rate for PCa by alterin...

    Jia-jie Lv, Lin-jie Zhang, **ang-Meng Kong, Yan Zhao, **n-yu Li in BMC Public Health (2024)

  9. No Access

    Article

    Remnant cholesterol and risk of incident hypertension: a population-based prospective cohort study

    Remnant cholesterol (RC) has been associated with atherosclerotic cardiovascular disease, but its relationship with hypertension remains unclear. This prospective cohort study aimed to investigate the associat...

    Da-Chuan Guo, **g-Wei Gao, **ang Wang, Zhi-Teng Chen in Hypertension Research (2024)

  10. Article

    Open Access

    A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology

    Impaired brain glucose metabolism is an early indicator of Alzheimer’s disease (AD); however, the fundamental mechanism is unknown. In this study, we found a substantial decline in isocitrate dehydrogenase 3β ...

    **n Wang, Qian Liu, Hai-tao Yu, Jia-zhao **e in Signal Transduction and Targeted Therapy (2024)

  11. Article

    Open Access

    Diet and lifestyle behaviours simultaneously act on frailty: it is time to move the threshold of frailty prevention and control forward

    To analyse the association among the simultaneous effects of dietary intake, daily life behavioural factors, and frailty outcomes in older Chinese women, we predicted the probability of maintaining physical ro...

    Shan-lan Yang, Lei Wu, He-lang Huang, Lang-lang Zhang, Yi-xin Chen in BMC Public Health (2024)

  12. Article

    Open Access

    METTL14 downregulation drives S100A4+ monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression

    Without intervention, a considerable proportion of patients with metabolism‐associated fatty liver disease (MAFLD) will progress from simple steatosis to metabolism‐associated steatohepatitis (MASH), liver fib...

    Yue-fan Wang, Wen-li Zhang, Zhi-xuan Li in Signal Transduction and Targeted Therapy (2024)

  13. Article

    Open Access

    Further clarification of cognitive processes of prospective memory in schizophrenia by comparing eye-tracking and ecologically-valid measurements

    The aim of this study is to compare ecologically-valid measure (the Cambridge Prospective Memory Test, CAMPROMPT) and laboratory measure (eye-tracking paradigm) in assessing prospective memory (PM) in individu...

    Hang Li, Qi Wang, Wen-Peng Hou, Dong-Yang Chen, Yu-Shen Ding in Schizophrenia (2024)

  14. No Access

    Article

    Naoxueshu Oral Liquid Accelerates Post-Craniotomy Hematoma Absorption in Patients: An Open-Label, Multicenter, and Randomized Controlled Trial

    To investigate whether Naoxueshu Oral Liquid (NXS) could promote hematoma absorption in post-craniotomy hematoma (PCH) patients.

    Qiu He, Fu-xin Lin, **-ye Su, Ling-yun Zhuo in Chinese Journal of Integrative Medicine (2024)

  15. Article

    Open Access

    Establishment of stellate ganglion block in mice

    There have been no reports on the successful implementation of stellate ganglion block (SGB) in mice.

    Qirui Duan, Ying Zhou, Juan Zhi, Quanle Liu, ** Xu in European Journal of Medical Research (2024)

  16. Article

    Open Access

    Risk assessment of imported malaria in China: a machine learning perspective

    Following China’s official designation as malaria-free country by WHO, the imported malaria has emerged as a significant determinant impacting the malaria reestablishment within China. The objective of this st...

    Shuo Yang, Ruo-yang Li, Shu-ning Yan, Han-yin Yang, Zi-you Cao in BMC Public Health (2024)

  17. Article

    Open Access

    Construction of a gene model related to the prognosis of patients with gastric cancer receiving immunotherapy and exploration of COX7A1 gene function

    GC is a highly heterogeneous tumor with different responses to immunotherapy, and the positive response depends on the unique interaction between the tumor and the tumor microenvironment (TME). However, the cu...

    Si-yu Wang, Yu-xin Wang, Ao Shen, in European Journal of Medical Research (2024)

  18. Article

    Open Access

    Association between drinking water quality and mental health and the modifying role of diet: a prospective cohort study

    Environmental factors play an important role in develo** mental disorders. This study aimed to investigate the associations of metal and nonmetal elements in drinking water with the risk of depression and an...

    Shuduo Zhou, Mintao Su, Peng Shen, Zongming Yang, Pengfei Chai in BMC Medicine (2024)

  19. No Access

    Article

    Pien Tze Huang Inhibits Migration and Invasion of Hepatocellular Carcinoma Cells by Repressing PDGFRB/YAP/CCN2 Axis Activity

    To investigate the effects of Pien Tze Huang (PZH) on the migration and invasion of HCC cells and underlying molecular mechanism.

    Zhi-yi Luo, Qi Tian, Niang-mei Cheng in Chinese Journal of Integrative Medicine (2024)

  20. No Access

    Article

    No Incidence of Liver Cancer Was Observed in A Retrospective Study of Patients with Aristolochic Acid Nephropathy

    To assess the risk of aristolochic acid (AA)-associated cancer in patients with AA nephropathy (AAN).

    Tao Su, Zhi-e Fang, Yu-ming Guo, Chun-yu Wang in Chinese Journal of Integrative Medicine (2024)

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