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Article
Hepatitis B virus core protein stabilizes RANGAP1 to upregulate KDM2A and facilitate hepatocarcinogenesis
As a vital component of the hepatitis B virus (HBV) nucleocapsid, HBV core protein (HBC) contributes to hepatocarcinogenesis. Here, we aimed to assess the effects of RANGAP1 and KDM2A on tumorigenesis induced ...
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Article
Open AccessConstruction of a gene model related to the prognosis of patients with gastric cancer receiving immunotherapy and exploration of COX7A1 gene function
GC is a highly heterogeneous tumor with different responses to immunotherapy, and the positive response depends on the unique interaction between the tumor and the tumor microenvironment (TME). However, the cu...
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Chapter and Conference Paper
Function-Based Synthesis of Combined Mechanisms by Clustering Fine-Grained Function Units in the Form Layer
Conceived functional hierarchies closely related to building blocks and the lack of sufficient and explicit knowledge to describe the relationship between a combining mechanism and its constituent mechanisms a...
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Chapter and Conference Paper
Effects of Kinematic Parameters on Planar 3-RPR PM’s Motion Stability at Singular Configurations
Inspired by the case that a running parallelogram mechanism can traverse the singular configuration without losing motion stability, parallel manipulator's (PM) motion stability at singular configurations corr...
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Article
Spatiotemporal evolution of tourism ecological security alerts: evaluation and trend prediction
Tourism ecological safety (TES) warning is of great significance for eco-environmental protection and low-carbon development. We constructed a early warning index system of TES for the Yangtze River Delta Urba...
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Article
HFD-exacerbated Metabolic Side Effects of Olanzapine Are Suppressed by ER Stress Inhibitor
Numerous schizophrenic patients are suffering from obesity primarily attributed to antipsychotic medication and poor dietary habits. This study investigated the progressive deterioration of olanzapine-induced ...
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Article
Open AccessAutonomous quantum error correction and fault-tolerant quantum computation with squeezed cat qubits
We propose an autonomous quantum error correction scheme using squeezed cat (SC) code against excitation loss in continuous-variable systems. Through reservoir engineering, we show that a structured dissipatio...
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Article
Corrosion behavior of additive-manufactured NiFeCrMo alloys in various corrosion media
To understand the corrosion performance of additive-manufactured Ni-based in various corrosion media during the actual engineering application environment, the corrosion properties of NiFeCrMo alloys were inve...
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Article
Open AccessHardwiring tissue-specific AAV transduction in mice through engineered receptor expression
The development of transgenic mouse models that express genes of interest in specific cell types has transformed our understanding of basic biology and disease. However, generating these models is time- and re...
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Article
Relationship between acrylamide and glycidamide hemoglobin adduct levels and osteoarthritis: a NHANES analysis
Osteoarthritis (OA) is the most prevalent degenerative joint disease, and acrylamide is a chemical produced when foods are processed at high temperatures. Recent epidemiological research linked acrylamide expo...
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Article
Microstructures and bio-corrosion resistances of as-extruded Mg–Ca alloys with ultra-fine grain size
Electrochemical and immersion tests were conducted to characterize the bio-corrosion resistance of as-extruded Mg–Ca binary alloys with submicron grain size. The microstructures were further characterized by o...
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Article
Open AccessMachine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors
The proper regulation of muscle stem cell (MuSC) fate by cues from the niche is essential for regeneration of skeletal muscle. How pro-regenerative niche factors control the dynamics of MuSC fate decisions rem...
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Article
Covalent organic framework in situ grown on Fe3O4 hollow microspheres for stir bar sorptive-dispersive microextraction of triazole pesticides
Based on covalent organic framework (COF) 1,3,5-tris-(4-formylphenyl)benzene-benzidine (TFPB-BD) in situ grown on Fe3O4 hollow microspheres and combined with gas chromatography-flame thermionic detector, a rapid ...
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Article
Research on titanium-copper explosive welding interface with different welding parameters
Vortex holes at the welding interface will affect the interface sealing performance of the explosive welding clad plate, so in the production process to choose the appropriate parameters to avoid the productio...
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Article
Experimental and numerical study on the explosive welding of niobium-steel
The aim of this work is to study the method of explosive welding to produce niobium-steel composite plate, which is used in nuclear industry equipment material manufacturing. The welding parameters were determ...
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Article
Open AccessPrimary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging
During aging, the regenerative capacity of muscle stem cells (MuSCs) decreases, diminishing the ability of muscle to repair following injury. We found that the ability of MuSCs to regenerate is regulated by th...
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Chapter and Conference Paper
Assistant Teaching Platform for Creative Mechanical Design Course
Innovative engineering education plays a vital role in promoting inclusive and sustainable industrialization worldwide. Creative Mechanical Design is a course open to senior students and graduate students for ...
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Article
Open AccessIntrinsic and induced quantum quenches for enhancing qubit-based quantum noise spectroscopy
Quantum sensing protocols that exploit the dephasing of a probe qubit are powerful and ubiquitous methods for interrogating an unknown environment. They have a variety of applications, ranging from noise mitig...
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Article
Cytochalasans and azaphilones: suitable chemotaxonomic markers for the Chaetomium species
The accurate taxonomic concept of the fungal Chaetomium species has been a hard work due to morphological similarity. Chemotaxonomy based on secondary metabolites is a powerful tool for taxonomical purposes, whic...
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Article
Open AccessSerum metabolomics in chickens infected with Cryptosporidium baileyi
Cryptosporidium baileyi is an economically important zoonotic pathogen that causes serious respiratory symptoms in chickens for which no effective control measures are currently available. An accumulating body of...
