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  1. No Access

    Article

    Solitary juvenile polyp of the rectum with intramucosal adenocarcinoma

    We describe a case of solitary juvenile polyp of the rectum with intramucosal adenocarcinoma. A 55-year-old man presented to our hospital for evaluation after a positive fecal occult blood test. Colonoscopy re...

    Kazuki Nagai, Uichiro Fuchizaki, Yoshimichi Ueda in Clinical Journal of Gastroenterology (2023)

  2. No Access

    Article

    Solitary extrahepatic hepatocellular carcinoma in vertebrae without a primary lesion in the liver might originate from bone marrow: a case report and new hypothesis based on a review of the literature and the latest findings

    Solitary extrahepatic hepatocellular carcinoma without a primary lesion in the liver is rare and unique. In such patients, in addition to hepatocellular carcinoma, hepatoid adenocarcinoma, hepatoid teratoma, a...

    Yukihiro Shirota, Yoshimichi Ueda, Katsuaki Sato in Clinical Journal of Gastroenterology (2022)

  3. No Access

    Article

    Complete remission after concurrent single-agent S-1 chemoradiotherapy for stage IIIB esophageal cancer: an autopsy case report

    Chemoradiotherapy regimens for patients with esophageal cancer intolerant to standard therapies remain to be established. The standard therapy for patients with stage II–III esophageal squamous cell carcinoma,...

    Jun Miyata, Masahide Yamazaki, Yoshimichi Ueda in Clinical Journal of Gastroenterology (2022)

  4. Article

    Open Access

    Primary pulmonary T-cell lymphoma with lung adenocarcinoma: a case report

    Primary pulmonary T-cell lymphoma is an extremely rare disease that is characterized by neoplastic proliferation of T-cell lymphocytes in the lung.

    Yutaka Takahara, Takashi Sakuma, Kazuaki Nishiki in Journal of Medical Case Reports (2019)

  5. Article

    Open Access

    FDG-PET/CT and diffusion-weighted imaging for resected lung cancer: correlation of maximum standardized uptake value and apparent diffusion coefficient value with prognostic factors

    Diffusion-weighted magnetic resonance imaging (DWI) is useful for detecting malignant tumors and the assessment of lymph nodes, as FDG-PET/CT is. But it is not clear how DWI influences the prognosis of lung ca...

    Katsuo Usuda, Aika Funasaki, Atsushi Sekimura, Nozomu Motono in Medical Oncology (2018)

  6. Article

    Open Access

    Prevention of glucocorticoid-associated osteonecrosis by intravenous administration of mesenchymal stem cells in a rabbit model

    Glucocorticoid-associated osteonecrosis is an intractable condition, making the establishment of preventative strategies of particular importance. Recently various studies using mesenchymal stem cells (MSC) ha...

    Shusuke Ueda, Miyako Shimasaki, Toru Ichiseki in BMC Musculoskeletal Disorders (2017)

  7. No Access

    Article

    High FDG uptake on PET is associated with negative cell-to-cell adhesion molecule E-cadherin expression in lung adenocarcinoma

    E-cadherin is a main cell-to-cell adhesion molecule. A negative expression of E-cadherin correlates with distant metastasis in lung cancer. Recently, it was reported that there is an association between FDG up...

    Kotaro Higashi, Yoshimichi Ueda, Miyako Shimasaki in Annals of Nuclear Medicine (2017)

  8. No Access

    Article

    Correlation of HIF-1α/HIF-2α expression with FDG uptake in lung adenocarcinoma

    Hypoxia is a key element involved in the development and progression of tumors. HIF-1α may transiently induce and mediate the response to acute and severe hypoxia, while HIF-2α may induce a longer response and...

    Kotaro Higashi, Toshiaki Yamagishi, Yoshimichi Ueda in Annals of Nuclear Medicine (2016)

  9. No Access

    Article

    Osteocytic cell necrosis is caused by a combination of glucocorticoid-induced Dickkopf-1 and hypoxia

    Osteonecrosis is a major glucocorticoid-induced complication in the orthopedics field. Despite the extensive researches, mechanisms underlining the glucocorticoid-induced osteonecrosis are largely unknown. Her...

    Shusuke Ueda, Toru Ichiseki, Yasuo Yoshitomi in Medical Molecular Morphology (2015)

  10. Article

    Open Access

    Relationship between vascular reactivity and expression of HMGB1 in a rat model of septic aorta

    High mobility group box 1 (HMGB1), a ubiquitous nuclear protein, induces several inflammatory diseases and functions as a fatal factor when released extracellularly. The effect of HMGB1 on vascular reactivity ...

    Satoshi Nishiike, Toshiaki Hiramatsu, Miharu Shiraishi in Journal of Anesthesia (2013)

  11. No Access

    Article

    Establishment of an animal model for delayed-onset muscle soreness after high-intensity eccentric exercise and its application for investigating the efficacy of low-load eccentric training

    Delayed-onset muscle soreness (DOMS) occurs after unaccustomed exercise and is particularly associated with eccentric exercise. Previous studies have proposed the use of a single bout of eccentric exercise to ...

    Teppei Munehiro, Katsuhiko Kitaoka, Yoshimichi Ueda in Journal of Orthopaedic Science (2012)

  12. No Access

    Article

    VEGF-A and its isoform VEGF121 mRNA expression measured by quantitative real-time RT-PCR: correlation with F-18 FDG uptake and aggressiveness of lung adenocarcinoma: preliminary study

    To investigate the correlation of vascular endothelial growth factor (VEGF) A and its isoform VEGF 121 mRNA expression with F-18 fluorodeoxyglucose (FDG) uptake and aggressiveness in lung adenocarcinoma.

    JianFei Guo, Kotaro Higashi, Yoshimichi Ueda in Annals of Nuclear Medicine (2011)

  13. No Access

    Article

    Prevention of steroid-induced osteonecrosis by intravenous administration of vitamin E in a rabbit model

    We focused on vitamins with marked antioxidant potency to see whether their use might prevent the development of steroid-induced osteonecrosis.

    Tomoaki Mikami, Toru Ichiseki, Ayumi Kaneuji in Journal of Orthopaedic Science (2010)

  14. No Access

    Article

    Correlation between glucose transporter-1 expression and 18F-fluoro-2-deoxyglucose uptake on positron emission tomography in lung cancer

    The aim of this study was to determine if glucose transporter-1 (Glut1) expression correlates with 18F-FDG (18F-fluoro-2-deoxyglucose) uptake on positron emission tomography (PET) in lung cancer and to examine th...

    Katsuo Usuda, Motoyasu Sagawa in General Thoracic and Cardiovascular Surgery (2010)

  15. No Access

    Article

    Assessment of VEGF-D expression measured by immunohistochemical staining and F-18 FDG uptake on PET as biological prognostic factors for recurrence in patients with surgically resected lung adenocarcinoma

    To assess whether the combined evaluation of vascular endothelial growth factor D (VEGF-D) expression and fluorodeoxyglucose (FDG) uptake correlates with lymph node metastasis and post-operative recurrence in ...

    Lina Zhang, Kotaro Higashi, Yasuhito Ishigaki in Annals of Nuclear Medicine (2010)

  16. No Access

    Article

    Organizing pneumonia with an enlarging tumor-like lesion: immunohistochemical study

    An 86-year-old woman was transferred to our department for investigation of an abnormal enlarging pulmonary shadow with vascular convergence. She had no respiratory symptoms or laboratory data suggesting infla...

    Motoyasu Sagawa, Yoshimichi Ueda in General Thoracic and Cardiovascular Surgery (2009)

  17. No Access

    Article

    Combined evaluation of preoperative FDG uptake on PET, ground-glass opacity area on CT, and serum CEA level: identification of both low and high risk of recurrence in patients with resected T1 lung adenocarcinoma

    Patients with the same pathological stage of lung adenocarcinoma display marked variability in postoperative recurrence. The aim of this study was to predict the postoperative prognosis in patients with small-...

    Kotaro Higashi, Tsutomu Sakuma, Kengo Ito in European Journal of Nuclear Medicine and M… (2009)

  18. No Access

    Article

    Intrapulmonary Solitary Fibrous Tumor Diagnosed by Immunohistochemical and Genetic Approaches: Report of a Case

    Although solitary fibrous tumors (SFTs) of the pleura are not uncommon, intrapulmonary SFTs are extremely rare. A 72-year-old woman was admitted to our hospital for an investigation of an enlarging intrapulmon...

    Motoyasu Sagawa, Yoshimichi Ueda, Fujitsugu Matsubara, Hiroshi Sakuma in Surgery Today (2007)

  19. No Access

    Article

    Extrauterine endometrial stromal sarcoma with JAZF1/JJAZ1 fusion confirmed by RT-PCR and interphase FISH presenting as an inguinal tumor

    Endometrial stromal sarcomas are rare malignant mesenchymal tumors that usually develop in the uterine corpus and occasionally arise at various extrauterine sites. This report describes the first case of prima...

    Katsuaki Sato, Yoshimichi Ueda, Junichi Sugaya, Mamoru Ozaki in Virchows Archiv (2007)

  20. No Access

    Article

    Sertoli cell tumor of the testis, not otherwise specified, presenting extensive hemorrhage and overexpression of α-methylacyl-CoA racemase (AMACR/P504S)

    Katsuaki Sato, Hironori Tachibana, Shojiroh Morinaga, Yoshimichi Ueda in Virchows Archiv (2007)

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