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Article
Open AccessAn ultra high-endurance memristor using back-end-of-line amorphous SiC
Integrating resistive memory or neuromorphic memristors into mainstream silicon technology can be substantially facilitated if the memories are built in the back-end-of-line (BEOL) and stacked directly above t...
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Article
Do social preferences increase the pro-environmental behavior of farmers? — empirical evidence from protected areas in China
Protected areas (PAs) are key areas for biodiversity conservation, and at the saµe tiµe they are also ecologically fragile areas. Therefore, proµoting farµers around PAs to practice pro−environµental behaviors...
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Article
Driving factors behind multiple populations
Star clusters were historically considered simple stellar populations, with all stars sharing the same age and initial chemical composition. However, the presence of chemical anomalies in globular clusters (GC...
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Article
Open AccessThe impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities
The telomere repetitive TTAGGG motif at the ends of chromosomes, serves to preserve genomic integrity and chromosomal stability. In turn, genomic instability is a hallmark of cancer—implicating telomere distur...
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Article
China’s high-quality economic development: a study of regional variations and spatial evolution
Based on the current reality of unbalanced and inadequate regional economic development in China, this study constructs a comprehensive index system to asses China’s economic development quality across six dim...
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Article
TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC
TRAF-interacting protein (TRAIP), an E3 ligase containing a RING domain, has emerged as a significant contributor to maintaining genome integrity and is closely associated with cancer. Our study reveals that T...
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Article
Open AccessLaparoscopic ureteroneocystostomy with bladder flap for benign ureteral stenosis: our initial experience
To present our experience with laparoscopic ureteroneocystostomy with bladder flap (LUCBF) for treating benign ureteral stenosis and evaluate its feasibility and efficacy. The clinical data of 27 patients with...
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Article
Open AccessDevelopment and application of Chinese medical ontology for diabetes mellitus
To develop a Chinese Diabetes Mellitus Ontology (CDMO) and explore methods for constructing high-quality Chinese biomedical ontologies.
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Article
Open AccessContextualizing the revised Patient Perception of Patient-Centeredness (PPPC-R) scale in primary healthcare settings: a validity and reliability evaluation study
An English version of the Patient Perception of Patient-Centeredness (PPPC) scale was recently revised, and it is necessary to test this instrument in different primary care populations.
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Open AccessCord blood-derived biologics lead to robust axonal regeneration in benzalkonium chloride-injured mouse corneas by modulating the Il-17 pathway and neuropeptide Y
Umbilical cord blood-derived therapeutics, such as serum (UCS) and platelet-rich plasma (UCPRP), are popular treatment options in clinical trials and can potentially be utilized to address a clinically unmet n...
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Article
Fabrication of MoS2 with Dual Defects of O-Do** and S-Vacancies for High-Efficiency Hydrogen Production
Develo** excellent electrocatalysts is a significant step in accelerating the widespread implementation of the electrochemical hydrogen evolution reaction (HER). MoS2 is one of the promising alternatives to pla...
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Article
High Figure of Merit Refractive Index Sensor Derived From the Axial Length Ratio of Elliptically Polarized Light of Chiral Plasmonic Structure Arrays
The refractive index sensor based on the Fano resonance effect (that is, Fano sensor) is one promising branch of plasmonic sensing applications owing to its narrow spectral line shape. Further improvement in t...
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Article
Open AccessComprehensive analysis of the clinical and biological significances of cholesterol metabolism in lower-grade gliomas
As a component of membrane lipids and the precursor of oxysterols and steroid hormones, reprogrammed cholesterol metabolism contributes to the initiation and progression of multiple cancers. Thus, we aim to fu...
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Article
Open AccessMolecular and clinical characterization of PTRF in glioma via 1,022 samples
Polymerase I and transcript release factor (PTRF) plays a role in the regulation of gene expression and the release of RNA transcripts during transcription, which have been associated with various human diseases....
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Article
Open AccessMesoporous polydopamine delivering 8-gingerol for the target and synergistic treatment to the spinal cord injury
In the treatment of spinal cord injury (SCI), the complex process of secondary injury is mainly responsible for preventing SCI repair or even exacerbating the injury. In this experiment, we constructed the 8-g...
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Article
The Prediction of Remaining Useful Life of Aluminum Reduction Cells Based on Improved Hidden Semi-Markov Model
An improved prediction algorithm of the hidden semi-markov model (HSMM) is proposed to predict the remaining useful life (RUL) of aluminum reduction cells (ARC). First, the degradation process of the ARC is an...
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Article
Open AccessConstruction of the first high-density genetic linkage map and QTL map** of flavonoid and leaf-size related traits in Epimedium
Leaves are the main medicinal organ in Epimedium herbs, and leaf flavonoid content is an important criterion of Epimedium herbs. However, the underlying genes that regulate leaf size and flavonoid content are unc...
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Article
Open AccessMaternal Western diet mediates susceptibility of offspring to Crohn’s-like colitis by deoxycholate generation
The Western dietary pattern, characterized by high consumption of fats and sugars, has been strongly associated with an increased risk of develo** Crohn’s disease (CD). However, the potential impact of mater...
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Article
Long non-coding RNA MSTRG.81401 short hairpin RNA relieves diabetic neuropathic pain and behaviors of depression by inhibiting P2X4 receptor expression in type 2 diabetic rats
Patients with diabetic neuropathic pain (DNP) experience immense physical and mental suffering, which is comorbid with other mental disorders, including major depressive disorder (MDD). P2X4 receptor, one of t...
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Article
Pathway for the low-carbon consumption pattern transition of residents in six eastern coastal provinces of China: using fuzzy-set qualitative comparative analysis with panel data
China has embarked on society-wide emission reduction initiatives to tackle the growing decarbonization pressures on national economic and social development. The low-carbon consumption pattern transition of t...