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Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to Hepatocyte Growth Factor

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  1. Article

    Open Access

    Standardization of molecular monitoring of CML: results and recommendations from the European treatment and outcome study

    Standardized monitoring of BCR::ABL1 mRNA levels is essential for the management of chronic myeloid leukemia (CML) patients. From 2016 to 2021 the European Treatment and Outcome Study for CML (EUTOS) explored the...

    Helen E. White, Matthew Salmon, Francesco Albano, Christina Søs Auður Andersen… in Leukemia (2022)

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  2. Article

    Open Access

    Impact of BCR::ABL1 transcript type on RT-qPCR amplification performance and molecular response to therapy

    Several studies have reported that chronic myeloid leukaemia (CML) patients expressing e14a2 BCR::ABL1 have a faster molecular response to therapy compared to patients expressing e13a2. To explore the reason for ...

    Matthew Salmon, Helen E. White, Hana Zizkova, Andrea Gottschalk, Eliska Motlova… in Leukemia (2022)

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  3. Article

    Open Access

    The prognostic and predictive value of ESR1 fusion gene transcripts in primary breast cancer

    In breast cancer (BC), recurrent fusion genes of estrogen receptor alpha (ESR1) and AKAP12, ARMT1 and CCDC170 have been reported. In these gene fusions the ligand binding domain of ESR1 has been replaced by the t...

    Silvia R. Vitale, Kirsten Ruigrok-Ritstier, A. Mieke Timmermans… in BMC Cancer (2022)

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  4. Article

    Open Access

    Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer

    Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect circulating tumor-derived EVs (ctEV...

    Silvia R. Vitale, Jean A. Helmijr, Marjolein Gerritsen, Hicret Coban… in BMC Cancer (2021)

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