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  1. Article

    Open Access

    The prognostic and predictive value of ESR1 fusion gene transcripts in primary breast cancer

    In breast cancer (BC), recurrent fusion genes of estrogen receptor alpha (ESR1) and AKAP12, ARMT1 and CCDC170 have been reported. In these gene fusions the ligand binding domain of ESR1 has been replaced by the t...

    Silvia R. Vitale, Kirsten Ruigrok-Ritstier, A. Mieke Timmermans in BMC Cancer (2022)

  2. Article

    Open Access

    Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer

    Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect circulating tumor-derived EVs (ctEV...

    Silvia R. Vitale, Jean A. Helmijr, Marjolein Gerritsen, Hicret Coban in BMC Cancer (2021)