88 Result(s)
within
English
Life Sciences
Cell Biology
Li **n Cheng
Article
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Article
Expression and colocalization of NADPH-diaphorase and heme oxygenase-2 in trigeminal ganglion and mesencephalic trigeminal nucleus of the rat
Carbon monoxide (CO) and nitric oxide (NO) are two endogenously produced gases that can function as second messenger molecules in the nervous system. The enzyme systems responsible for CO and NO biosynthesis a...
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Seed, cutting and air-layering reproductive inefficiency of noxious woody vine Merremia biosiana and its implications for management strategy
Merremia boisiana (Gagnep) van Ooststr. is a noxious fast growing woody vine and is able to grow overtop other plants, causing the death of plants underneath and forming monospecies stand...
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Molecular cloning and function assay of a chalcone isomerase gene (GbCHI) from Ginkgo biloba
Chalcone isomerase (CHI, EC 5.5.1.6) is one of the key enzymes in the flavonoid biosynthesis pathway catalyzing the stereospecific isomerization of chalcones into their corresponding (2S)-flavanones. In this i...
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Heterologous expression of the Arabidopsis DREB1A/CBF3 gene enhances drought and freezing tolerance in transgenic Lolium perenne plants
The dehydration-responsive element binding proteins (DREB1)/C-repeat (CRT) binding factors (CBF) function as transcription factors and play an important role in agricultural biotechnology and molecular biology...
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Effect of Low-Intensity Pulsed Ultrasound on MMP-13 and MAPKs Signaling Pathway in Rabbit Knee Osteoarthritis
We evaluated the effect of low-intensity pulsed ultrasound (LIPUS) on MMP-13 and MAPKs expression in rabbit knee osteoarthritis (OA). For this purpose, 18 New Zealand white rabbits were randomly and equally di...
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Open AccessCardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice
Recent studies have begun to reveal critical roles of microRNAs (miRNAs) in the pathogenesis of cardiac hypertrophy and dysfunction. In this study, we tested whether a transforming growth factor-β (TGF-β)-regu...
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Claudin 6: a novel surface marker for characterizing mouse pluripotent stem cells
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Open AccessMitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway
Cofilin is a member of the actin depolymerizing factor (ADF)/cofilin family, which regulates actin dynamics. Increasing evidence suggests that mitochondrial translocation of cofilin appears necessary for the r...
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A novel translocation event leads to a recombinant stable chromosome with interrupted centromeric domains in rice
Rice (Oryza sativa L.) centromeres are composed of 155-bp satellite repeats (CentO), centromere-specific retrotransposon (CRR), and a variety of other repeats. Previous studies have shown that CentO and CRR eleme...
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MRE11 is required for homologous synapsis and DSB processing in rice meiosis
Mre11, a conserved protein found in organisms ranging from yeast to multicellular organisms, is required for normal meiotic recombination. Mre11 interacts with Rad50 and Nbs1/Xrs2 to form a complex (MRN/X) tha...
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Overexpression of the Mesenchymal Stem Cell Cxcr4 Gene in Irradiated Mice Increases the Homing Capacity of These Cells
The efficiency of the intravascular delivery of mesenchymal stem cells (MSCs) homing to bone marrow has been largely limited. This study aimed to evaluate the homing efficacy in irradiated mice of MSCs that ha...
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An R2R3-MYB transcription factor as a negative regulator of the flavonoid biosynthesis pathway in Ginkgo biloba
Flavonoids are secondary metabolites that contribute substantially to the quality of Ginkgo biloba. Plant flavonoid accumulation is controlled by transcriptional regulation of the genes that encode the biosynthet...
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Fertile introgression products generated via somatic hybridization between wheat and Thinopyrum intermedium
Fertile hybrids were produced with genetic material transferred from Th. intermedium into a wheat background and supply a source of genetic...
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Hydrogen peroxide primes heart regeneration with a derepression mechanism
While the adult human heart has very limited regenerative potential, the adult zebrafish heart can fully regenerate after 20% ventricular resection. Although previous reports suggest that developmental signali...
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Isolation and functional characterization of a novel rice constitutive promoter
A novel rice constitutive promoter (P OsCon1 ) was isolated. The molecular mechanism of the promoter activity was inv...
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ABI-like transcription factor gene TaABL1 from wheat improves multiple abiotic stress tolerances in transgenic plants
The phytohormone abscisic acid (ABA) plays crucial roles in adaptive responses of plants to abiotic stresses. ABA-responsive element binding proteins (AREBs) are basic leucine zipper transcription factors that...
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Open AccessHuman mesenchymal stem cells possess different biological characteristics but do not change their therapeutic potential when cultured in serum free medium
Mesenchymal stem cells (MSCs) are widely investigated in clinical researches to treat various diseases. Classic culture medium for MSCs, even for clinical use, contains fetal bovine serum. The serum-containing...
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Open AccessCell-bricks based injectable niche guided persistent ectopic chondrogenesis of bone marrow-derived mesenchymal stem cells and enabled nasal augmentation
Develo** cartilage constructs with injectability, appropriate matrix composition and persistent cartilaginous phenotype remains an enduring challenge in cartilage repair. Bone marrow derived mesenchymal stem...
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Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways
Cisplatin is a first-line chemotherapy drug against ovarian cancer. However, its strong toxic side effects and the development of cisplatin resistance in human cancer cells seriously influence the effects of c...
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Open AccessGenes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor β
Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and induced pluripotent stem cell reprogramming. We hypoth...
