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    Article

    Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

    The past decade has witnessed hundreds of reports declaring or refuting genetic association with putative Alzheimer disease susceptibility genes. This wealth of information has become increasingly difficult to...

    Lars Bertram, Matthew B McQueen, Kristina Mullin, Deborah Blacker in Nature Genetics (2007)

  2. Article

    Open Access

    Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families

    In family-based association analysis, each family is typically ascertained from a single proband, which renders the effects of ascertainment bias heterogeneous among family members. This is contrary to case–co...

    Suyeon Park, Sungyoung Lee, Young Lee, Christine Herold in BMC Medical Genetics (2015)

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    Article

    Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease

    Alzheimer’s disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous, with a broad range of rates of cognitive decline1. The spread of tau aggregates (neurofibrillary ta...

    Simon Dujardin, Caitlin Commins, Aurelien Lathuiliere, Pieter Beerepoot in Nature Medicine (2020)

  4. Article

    Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease

    A Correction to this paper has been published: https://doi.org/10.1038/s41591-021-01251-7.

    Simon Dujardin, Caitlin Commins, Aurelien Lathuiliere, Pieter Beerepoot in Nature Medicine (2021)