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Isotoosendanin inhibits triple-negative breast cancer metastasis by reducing mitochondrial fission and lamellipodia formation regulated by the Smad2/3-GOT2-MYH9 signaling axis

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  1. Article

    Editorial Expression of Concern: Deacetylation of cortactin by SIRT1 promotes cell migration

    Y. Zhang, M. Zhang, H. Dong, S. Yong, X. Li, N. Olashaw, P. A. Kruk in Oncogene (2024)

  2. Article

    Open Access

    Correction: Role of hypoxia-mediated pyroptosis in the development of extending knee joint contracture in rats

    Quan-Bing Zhang, Lei Huo, Mian Li, Rui Zhang in European Journal of Medical Research (2024)

  3. Article

    Open Access

    Correction: A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology

    **n Wang, Qian Liu, Hai-tao Yu, Jia-zhao **e in Signal Transduction and Targeted Therapy (2024)

  4. Article

    Open Access

    Sodium selenite attenuates inflammatory response and oxidative stress injury by regulating the Nrf2/ARE pathway in contrast-induced acute kidney injury in rats

    Contrast-induced acute kidney injury (CI-AKI) is an acute renal complication that occurs after intravascular contrast agent administration. Sodium selenite (SS) is an inorganic source of Se and has potent anti...

    Haiyan **ang, Qianlin Tan, Yun Zhang, Yan Wu, Yaling Xu, Yuanhao Hong in BMC Nephrology (2024)

  5. Article

    Open Access

    Association of cord blood Ang-1 and sCD105 levels with bronchopulmonary dysplasia in preterm infants

    To investigate the relationship between cord blood levels of Angiopoietin-1 (Ang-1) and S-endoglin (sCD105) and bronchopulmonary dysplasia (BPD) in preterm infants.

    **gyun Yang, Yun Wang, Yixin Wu, Hailing Fan, Ouxuan **, Liwei Tang in BMC Pediatrics (2024)

  6. Article

    Open Access

    Assessing the suitability of video-assisted anal fistula treatment for obese patients compared to conventional surgery: a question worth investigating

    Video-assisted anal fistula treatment (VAAFT) is an innovative surgical approach enabling the direct visualization of the fistula tract structure. This study aims to assess the efficacy of VAAFT in comparison ...

    **ao-Li Tang, Zi-Yang Xu, Jun Yang, Zhe Yang in International Journal of Colorectal Disease (2024)

  7. Article

    Open Access

    CD147 TagSNP is associated with the vulnerability to lung cancer in the Chinese population: a case–control study

    Lung cancer, with its high morbidity and mortality, presents a major significant public health challenge. CD147, linked to cancer progression and metastasis, is a promising therapeutic target, including for lu...

    Yuning **e, Chu Huang, **anlei Zhou, Hongjiao Wu, Ang Li, Xuemei Zhang in Discover Oncology (2024)

  8. Article

    Open Access

    ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study

    ISIS 449884, a 2′-O-methoxyethyl antisense oligonucleotide that targets the glucagon receptor (GCGR), has demonstrated an ability to reduce hepatic glucose output and lower the blood glucose level. The primary ob...

    Linong Ji, Leili Gao, Zhikai Feng, Guoliang Chen, **g Fu, Erin Morgan in Diabetes Therapy (2024)

  9. Article

    Open Access

    Map** alternative splicing events in colorectal cancer

    Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal splicing events, especially alternative splicing (AS) event...

    Yifeng Zheng, Guoqiang Zhong, Qiuyu Song, Haonan Zhang, Shan** Wang in Discover Oncology (2024)

  10. Article

    Open Access

    Imaging-based body fat distribution and diabetic retinopathy in general US population with diabetes: an NHANES analysis (2003–2006 and 2011–2018)

    Limited studies have investigated the correlation between fat distribution and the risk of diabetic retinopathy (DR) in the general population with diabetes. The relationship between obesity and DR remains inc...

    Chenxin Li, Yili Zhang, Yujie Wang, Chufeng Gu, Bo Li, Mingming Ma in Nutrition & Diabetes (2024)

  11. Article

    Open Access

    Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study

    Neoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response varies greatly among individuals, how to select the optimal candid...

    Junhao Zhang, Ruiqing Liu, Xujian Wang in Journal of Cancer Research and Clinical On… (2024)

  12. Article

    Open Access

    Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma

    Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...

    Bao-Ye Sun, Dai Zhang, Wei Gan, **g-Fang Wu in Journal of Cancer Research and Clinical On… (2024)

  13. Article

    Open Access

    Uric acid to albumin ratio as a novel predictor for coronary slow flow phenomenon in patients with chronic coronary syndrome and non-obstructive coronary arteries

    The plasma uric acid to albumin ratio (UAR) is considered as a novel indicator for Inflammation. However, the association between UAR and coronary slow flow phenomenon (CSFP) remains unclear.

    **ao-jiao Zhang, Ai-jie Hou, Bo Luan, Cheng-fu Wang in BMC Cardiovascular Disorders (2024)

  14. Article

    Open Access

    Differences of clinical phenotype between familial and sporadic Crohn’s disease in East China

    Family history is one of the strongest risk factors for inflammatory bowel diseases (IBD) while studies about the clinical phenotype of familial IBD are limited. This study aimed to compare the phenotypic feat...

    Siyuan Dong, **aoxia **ang, Yu Zhang in International Journal of Colorectal Disease (2024)

  15. Article

    Open Access

    LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway

    Long noncoding RNAs (lncRNAs) exert a significant influence on various cancer-related processes through their intricate interactions with RNAs. Among these, lncRNA ZFAS1 has been implicated in oncogenic roles ...

    Baoyang Luo, Lin Zhuang, Ju Huang in Journal of Cancer Research and Clinical On… (2024)

  16. Article

    Open Access

    Metagenomic next-generation sequencing promotes diagnosis and treatment of Pneumocystis jirovecii pneumonia in non-HIV infected children: a retrospective study

    Metagenomic next-generation sequencing (mNGS) excels in diagnosis of infection pathogens. We aimed to evaluate the performance of mNGS for the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in non-HIV infect...

    Zhenyu Zhang, Tingyan Liu, Meixiu Ming, Meili Shen, Yi Zhang in BMC Pulmonary Medicine (2024)

  17. Article

    Open Access

    The value of deep learning-based X-ray techniques in detecting and classifying K-L grades of knee osteoarthritis: a systematic review and meta-analysis

    Knee osteoarthritis (KOA), a prevalent degenerative joint disease, is primarily diagnosed through X-ray imaging. The Kellgren-Lawrence grading system (K-L) is the gold standard for evaluating KOA severity thro...

    Haoming Zhao, Liang Ou, Ziming Zhang, Le Zhang, Ke Liu, Jianjun Kuang in European Radiology (2024)

  18. Article

    Open Access

    Decreased levels of PTCSC3 promote the deterioration of prostate cancer and affect the prognostic outcome of patients through sponge miR-182-5p

    Prostate cancer, characterized by its insidious onset and short overall survival, and has seen a rise in incidence over recent decades. This study aims to investigate the expression and molecular mechanism of ...

    Lin Cheng, Shuhui Li, Deqi Jiang, Rongkai Sun, Yueshan Wang, Jianchao Zhang in BMC Urology (2024)

  19. Article

    Open Access

    An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

    To explore the role of GAB2 in pan-cancer based on bioinformatics analysis.

    Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang in Discover Oncology (2024)

  20. Article

    Open Access

    Good outcome with conservative treatment of delayed spinal epidural hematoma following combined spinal-epidural anesthesia: a rare case report

    Delayed spinal epidural hematoma (SEH) following central neuraxial block (CNB) is a rare but serious complication. The underlying causes of SEH associated with neuraxial anesthesia are still unclear. Furthermo...

    Hui Yao, Xuejie Li, Shize Leng, Hui Zhang in BMC Anesthesiology (2024)

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