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Article
Open AccessCombining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies
The standard approach to the analysis of genome-wide association studies (GWAS) is based on testing each position in the genome individually for statistical significance of its association with the phenotype u...
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Article
Open AccessGenomic analysis of the blood attributed to Louis XVI (1754–1793), king of France
A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754–1793) after his beheading but recen...
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Article
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
A complete pre-agricultural European human genome from a ∼7,000-year-old Mesolithic skeleton suggests the existence of a common genomic signature across western and central Eurasia from the Upper Paleolithic t...