55 Result(s)
within
Article
Jiwang Zhang
English
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Article
Open AccessCaspase 8 deletion causes infection/inflammation-induced bone marrow failure and MDS-like disease in mice
Myelodysplastic syndromes (MDS) are a heterogeneous group of pre-leukemic hematopoietic disorders characterized by cytopenia in peripheral blood due to ineffective hematopoiesis and normo- or hypercellularity ...
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Open AccessDetermination of viable myocardium through delayed enhancement cardiac magnetic resonance imaging combined with 18F-FDG PET myocardial perfusion/metabolic imaging before CABG
Purpose: Study aims to investigate the consistency of delayed enhancement cardiac magnetic resonance imaging (DE-CMR) and 18F-FDG PET myocardial imaging in evaluating myocardial viability before CABG. Methods: Th...
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Residual Stress Relaxation Behaviors and Fatigue Strength of Micro-Shot Peened EA4T Axle Steel under Constant and Variable Loading
To investigate the residual stress relaxation behaviors and fatigue strength, EA4T steel specimens are subjected to micro-shot peening (MSP), and part of them are isothermally annealed at 250 °C for 2 hours. F...
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Thermal Stress Field and Microstructure Evolution of Ti-6Al-4V Fabricated by Laser Engineered Net Sha**
To investigate the thermal stress field and microstructure evolution of Ti-6Al-4V alloy component produced by laser engineered net sha** (LENS), numerical simulations are performed at both macroscale and mes...
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Investigation of plasma electrolytic oxidation coating formed on two Al–Si–Mg alloys via advanced X-ray computed tomography
In this work, the influence of Si concentration on the microstructure and growth of plasma electrolytic oxidation (PEO) coatings on two types of Al–Si–Mg aluminum alloys were investigated. we utilized a multis...
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Differences of cadmium uptake and accumulation in roots of two maize varieties (Zea mays L.)
Different maize varieties respond differentially to cadmium (Cd) stress. As the first organ in contact with the soil, the response of the root is particularly important. However, the physiological mechanisms t...
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Open AccessPAI-1 regulates AT2-mediated re-alveolarization and ion permeability
Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung ...
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Nitrogen rate effects reproductive development and grain set of summer maize by influencing fatty acid metabolism
The developmental status of the male and female spike determines grain number (GN) per ear and yield. A better understanding of the effect of N on male and female spike differentiation and GN formation could h...
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Spraying S-ABA Can Alleviate the Growth Inhibition of Corn (Zea mays L.) Under Water-Deficit Stress
Drought stress (water-deficit stress) is an important abiotic factor affecting the growth and yield of maize, which threatens food security worldwide. S-Abscisic acid (S-ABA) is widely used to alleviate plant ...
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Open AccessMaize (Zea mays L.) responses to salt stress in terms of root anatomy, respiration and antioxidative enzyme activity
Soil salt stress is a problem in the world, which turns into one of the main limiting factors hindering maize production. Salinity significantly affects root physiological processes in maize plants. There are ...
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Open AccessRole of TET dioxygenases in the regulation of both normal and pathological hematopoiesis
The family of ten-eleven translocation dioxygenases (TETs) consists of TET1, TET2, and TET3. Although all TETs are expressed in hematopoietic tissues, only TET2 is commonly found to be mutated in age-related clon...
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Correction to: Root anatomical phenotypes related to growth under low nitrogen availability in maize (Zea mays L.) hybrids
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Molecular mechanisms by which splice modulator GEX1A inhibits leukaemia development and progression
Splice modulators have been assessed clinically in treating haematologic malignancies exhibiting splice factor mutations and acute myeloid leukaemia. However, the mechanisms by which such modulators repress le...
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Increasing genomic discovery in newly diagnosed multiple myeloma: defining disease biology and its correlation to risk
Our understanding of MM genomics has expanded rapidly in the past 5–10 years as a consequence of cytogenetic analyses obtained in routine clinical practice as well as the ability to perform whole-exome/genome ...
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Mechanisms that regulate the activities of TET proteins
The ten–eleven translocation (TET) family of dioxygenases consists of three members, TET1, TET2, and TET3. All three TET enzymes have Fe+2 and α-ketoglutarate (α-KG)-dependent dioxygenase activities, catalyzing t...
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Open AccessHigh-risk disease in newly diagnosed multiple myeloma: beyond the R-ISS and IMWG definitions
Multiple myeloma (MM) is an acquired malignant plasma cell disorder that develops late in life. Although progression free and overall survival has improved across all age, race, and ethnic groups, a subset of ...
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Root anatomical phenotypes related to growth under low nitrogen availability in maize (Zea mays L.) hybrids
To realize the so-called “Second Green Revolution”, it is imperative to study the roots of crop plants, and identify those traits that improve the efficiency of nitrogen (N) acquisition. We aimed to evaluate h...
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Dynamic Response Simulation of the HTS Bulk Over an Actual Permanent Magnet Guideway Using Different E-J Relationships
High temperature superconducting (HTS) maglev transportation has provided a new development direction for high-speed and ultra-high-speed rail transit. In order to promote the development of HTS materials in t...
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Open AccessThe role of TBK1 in cancer pathogenesis and anticancer immunity
The TANK-binding kinase 1 (TBK1) is a serine/threonine kinase belonging to the non-canonical inhibitor of nuclear factor-κB (IκB) kinase (IKK) family. TBK1 can be activated by pathogen-associated molecular pat...
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RIPK3 signaling and its role in the pathogenesis of cancers
RIPK3 (receptor-interacting protein kinase 3) is a serine/threonine-protein kinase. As a key component of necrosomes, RIPK3 is an essential mediator of inflammatory factors (such as TNFα-tumor necrosis factor ...
