6 Result(s)
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Article
Gloria Martrus
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Article
CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation
Gastrointestinal infections are a major cause for serious clinical complications in infants. The induction of antibody responses by B cells is critical for protective immunity against infections and requires C...
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A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44
Natural killer (NK) cells can recognize virus-infected and stressed cells1 using activating and inhibitory receptors, many of which interact with HLA class I. Although early studies also suggested a functional im...
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Open AccessHobit expression by a subset of human liver-resident CD56bright Natural Killer cells
Immune responses show a high degree of tissue specificity shaped by factors influencing tissue egress and retention of immune cells. The transcription factor Hobit was recently shown to regulate tissue-residen...
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Open AccessPeptide-specific engagement of the activating NK cell receptor KIR2DS1
The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this re...
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Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1
The activating NK cell receptor KIR3DS1 has been linked to the outcome of various human diseases, yet a ligand that would account for its biological effects has remained unknown. Altfeld and colleagues establi...
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Open AccessChanges in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture
Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence of HIV-1 that is observe...
