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  1. No Access

    Article

    Mechanism of high-mannose N-glycan breakdown and metabolism by Bifidobacterium longum

    Bifidobacteria are early colonizers of the human gut and play central roles in human health and metabolism. To thrive in this competitive niche, these bacteria evolved the capacity to use complex carbohydrates...

    Rosa L. Cordeiro, Camila R. Santos, Mariane N. Domingues in Nature Chemical Biology (2023)

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    Article

    Degradation of Sugarcane Bagasse by Cockroach Consortium Bacteria

    The development of new lignocellulosic enzyme cocktails to digest raw material for the successful production of biofuels still represents great economic and scientific challenges. The aim of this study was the...

    Danielle B. Carvalho, Douglas A. Paixão, Gabriela F. Persinoti in BioEnergy Research (2022)

  3. Article

    Open Access

    Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides

    The largest living rodent, capybara, can efficiently depolymerize and utilize lignocellulosic biomass through microbial symbiotic mechanisms yet elusive. Herein, we elucidate the microbial community compositio...

    Lucelia Cabral, Gabriela F. Persinoti, Douglas A. A. Paixão in Nature Communications (2022)

  4. Article

    Open Access

    Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors

    Xyloglucans are highly substituted and recalcitrant polysaccharides found in the primary cell walls of vascular plants, acting as a barrier against pathogens. Here, we reveal that the diverse and economically ...

    Plinio S. Vieira, Isabela M. Bonfim, Evandro A. Araujo in Nature Communications (2021)

  5. Article

    Publisher Correction: Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Camila R. Santos, Pedro A. C. R. Costa, Plínio S. Vieira in Nature Chemical Biology (2020)

  6. No Access

    Article

    Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family

    The fundamental and assorted roles of β-1,3-glucans in nature are underpinned on diverse chemistry and molecular structures, demanding sophisticated and intricate enzymatic systems for their processing. In thi...

    Camila R. Santos, Pedro A. C. R. Costa, Plínio S. Vieira in Nature Chemical Biology (2020)

  7. Article

    Open Access

    Novel redox-active enzymes for ligninolytic applications revealed from multiomics analyses of Peniophora sp. CBMAI 1063, a laccase hyper-producer strain

    The repertoire of redox-active enzymes produced by the marine fungus Peniophora sp. CBMAI 1063, a laccase hyper-producer strain, was characterized by omics analyses. The genome revealed 309 Carbohydrate-Active En...

    Lívia B. Brenelli, Gabriela F. Persinoti, João Paulo L. Franco Cairo in Scientific Reports (2019)

  8. No Access

    Article

    Microbial Communities of the Gut and Nest of the Humus- and Litter-Feeding Termite Procornitermes araujoi (Syntermitinae)

    The evolution of the symbiotic association with microbes allowed termites to decompose ingested lignocellulose from plant-derived substrates, including herbivore dung and soil humus. Representatives of the Syn...

    Edimar A. Moreira, Thabata M. Alvarez, Gabriela F. Persinoti in Current Microbiology (2018)

  9. Article

    Open Access

    Lignolytic-consortium omics analyses reveal novel genomes and pathways involved in lignin modification and valorization

    Lignin is a heterogeneous polymer representing a renewable source of aromatic and phenolic bio-derived products for the chemical industry. However, the inherent structural complexity and recalcitrance of ligni...

    Eduardo C. Moraes, Thabata M. Alvarez, Gabriela F. Persinoti in Biotechnology for Biofuels (2018)

  10. Article

    Open Access

    The impact of chromatin remodelling on cellulase expression in Trichoderma reesei

    Trichoderma reesei is used for industry-scale production of plant cell wall-degrading enzymes, in particular cellulases, but also xylanases. The expression of the encoding genes was so...

    Thiago M. Mello-de-Sousa, Alice Rassinger, Marion E. Pucher in BMC Genomics (2015)

  11. Article

    Open Access

    Comparative metabolism of cellulose, sophorose and glucose in Trichoderma reeseiusing high-throughput genomic and proteomic analyses

    The filamentous fungus Trichoderma reesei is a major producer of lignocellulolytic enzymes utilized by bioethanol industries. However, to achieve low cost second generation bioethanol production on an industrial ...

    Lilian dos Santos Castro, Wellington Ramos Pedersoli in Biotechnology for Biofuels (2014)