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Article
Mechanism of high-mannose N-glycan breakdown and metabolism by Bifidobacterium longum
Bifidobacteria are early colonizers of the human gut and play central roles in human health and metabolism. To thrive in this competitive niche, these bacteria evolved the capacity to use complex carbohydrates...
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Article
Open AccessGut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides
The largest living rodent, capybara, can efficiently depolymerize and utilize lignocellulosic biomass through microbial symbiotic mechanisms yet elusive. Herein, we elucidate the microbial community compositio...
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Article
Open AccessTwo distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations
Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we kinetically and mechanistically describe ...
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Article
Publisher Correction: Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family
The fundamental and assorted roles of β-1,3-glucans in nature are underpinned on diverse chemistry and molecular structures, demanding sophisticated and intricate enzymatic systems for their processing. In thi...
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Article
Open AccessIdentification of putative TAL effector targets of the citrus canker pathogens shows functional convergence underlying disease development and defense response
Transcriptional activator-like (TAL) effectors, formerly known as the AvrBs3/PthA protein family, are DNA-binding effectors broadly found in Xanthomonas spp. that transactivate host genes upon injection via the b...