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Article
Livin promotes Smac/DIABLO degradation by ubiquitin–proteasome pathway
Livin, a member of the inhibitor of apoptosis protein (IAP) family, encodes a protein containing a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain. It has been reported that L...
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Article
Construction of Small-Caliber, Polydiaxanone Cyclohexanone Vascular Stents
Objective of this article is to construct and characterize a three-layered small-caliber, artificial vascular stent. The outer layer of the stent consisted of small intestine submucosa (SIS), the middle layer ...
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Article
Characterization of the Inhibition of Vein Graft Intimal Hyperplasia by a Biodegradable Vascular Stent
Characterization of biodegradable stent vein graft thickening. Polydioxanone vascular sutures (PDSs) were used in a biodegradable arteriovenous bypass model. Twenty-four rabbits underwent carotid interposition...
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Article
Quantitative proteomics analysis of parthenogenetically induced pluripotent stem cells
Parthenogenetic embryonic stem (pES) cells isolated from parthenogenetic activation of oocytes and embryos, also called parthenogenetically induced pluripotent stem cells, exhibit pluripotency evidenced by both i...
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Article
Open AccessCochaperonin CPN20 negatively regulates abscisic acid signaling in Arabidopsis
Previous study showed that the magnesium-protoporphyrin IX chelatase H subunit (CHLH/ABAR) positively regulates abscisic acid (ABA) signaling. Here, we investigated the functions of a CHLH/ABAR interaction pro...
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Article
Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis
Non-CG methylation is abundant in plants, but its functions are poorly understood. A new study has uncovered the contributions of each non-CG methyltransferase, including the poorly characterized methyltransfe...
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Article
Physicochemical properties and membrane biofouling of extra-cellular polysaccharide produced by a Micrococcus luteus strain
The physicochemical properties of the extra-cellular polysaccharide (EPS) produced by a Micrococcus luteus strain, a dominating strain isolated from membrane biofouling layer, were determined in t...
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Article
Sphingomonas flavus sp. nov. isolated from road soil
A yellow-colored, Gram-negative, strictly aerobic, non-motile, rod-shaped bacterium, designated THG-MM5T, was isolated from road soil in Yongin-si, Gyeonggi-do, Republic of Korea. Based on 16S rRNA gene sequence,...
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Article
Assessment of the Cadmium Exposure in the Blood, Diet, and Water of the Pumi People in Yunnan, China
Cadmium (Cd) is considered as one of the most toxic and carcinogenic heavy metals. Accumulation of Cd in the human body can cause multiorgan dysfunction. Long-term irrational mining activities have led to seri...
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Article
Acinetobacter plantarum sp. nov. isolated from wheat seedlings plant
Strain THG–SQM11T, a Gram-negative, aerobic, non-motile, coccus-shaped bacterium, was isolated from wheat seedlings plant in P. R. China. Strain THG–SQM11T was closely related to members of the genus Acinetobact...
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Article
Prognostic significance of FLT3-ITD in pediatric acute myeloid leukemia: a meta-analysis of cohort studies
The purpose of the study was to assess the effect of the internal tandem duplication in FMS-like tyrosine kinase 3 (FLT3-ITD) on the outcome in pediatric acute myeloid leukemia (AML) patients. We identified el...
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Article
Open AccessPhospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells
Cancer cells utilize flexible metabolic programs to maintain viability and proliferation under stress conditions including nutrient deprivation. Here we report that phospholipase D1 (PLD1) participates in the ...
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Article
Expression and functional activity of bitter taste receptors in primary renal tubular epithelial cells and M-1 cells
The kidney is essential in the maintenance of in vivo homeostasis by body fluid and electrolyte conservation and metabolic waste removal. Previously, we reported the expression of a novel G protein family (Tas...
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Article
RETRACTED ARTICLE: FoxM1-mediated RFC5 expression promotes temozolomide resistance
Although methylguanine-DNA-methyltransferase (MGMT) plays an important role in resistance to temozolomide (TMZ) in glioma, 40% of gliomas with MGMT inactivation are still resistant to TMZ. The underlying mecha...
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Article
Open AccessbFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
Transient global cerebral ischemia (tGCI) is a cerebrovascular disorder that can cause apoptotic neuronal damage and functional deficits. Basic fibroblast growth factor (bFGF) was reported to be highly express...
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Article
Open AccessA novel allele of TaGW2-A1 is located in a finely mapped QTL that increases grain weight but decreases grain number in wheat (Triticum aestivum L.)
A novel TaGW2-A1 allele was identified from a stable, robust QTL region, which is pleiotropic for thousand grain weight, grain number per spike, and grain morphometric parameters in wheat.
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Article
Open AccessMesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis
Crohn’s disease (CD) is a chronic inflammatory bowel disease that is difficult to treat. However, previous preclinical and clinical studies have shown that mesenchymal stromal cells (MSCs) are a promising ther...
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Article
Open AccessFoot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression
Nucleoside diphosphate kinase 1 (NME1) is well-known as a tumor suppressor that regulates p53 function to prevent cancer metastasis and progression. However, the role of NME1 in virus-infected cells remains un...
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Article
Structural chromosome rearrangements and polymorphisms identified in Chinese wheat cultivars by high-resolution multiplex oligonucleotide FISH
High-resolution multiplex oligonucleotide FISH revealed the frequent occurrence of structural chromosomal rearrangements and polymorphisms in widely grown wheat cultivars and their founders.
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Article
Open AccessNDRG2 suppression as a molecular hallmark of photoreceptor-specific cell death in the mouse retina
Photoreceptor cell death is recognized as the key pathogenesis of retinal degeneration, but the molecular basis underlying photoreceptor-specific cell loss in retinal damaging conditions is virtually unknown. ...