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Article
A Structured Cam-Clay Model with a Damage Variable
A plastic constitutive model, namely a structured Cam-clay model with a damage variable, is here established based on the modified Cam-clay model. The resultant compression curve of undisturbed soil is simplif...
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Article
Roots of Cynodon dactylon increase gas permeability and gas diffusion coefficient of highly compacted soils
This study experimentally investigated the short-term (about 6 months) effects of roots of Cynodon dactylon on the gas permeability and gas diffusion coefficient of soils with different degrees of compaction.
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Article
Mechanical Anisotropy of the Columnar Jointed Rock Mass Under Unloading Conditions
The mechanical properties of a columnar jointed rock mass (CJRM) under loading and unloading conditions differ appreciably. The CJRM at the Baihetan Hydropower Station has a distinct type of joint and a self-o...
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Article
Status and initial physics performance studies of the MPD experiment at NICA
The Nuclotron-based Ion Collider fAcility (NICA) is under construction at the Joint Institute for Nuclear Research (JINR), with commissioning of the facility expected in late 2022. The Multi-Purpose Detector (...
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Article
Correction to: Chemical Speciation and Interaction Mechanism of U in “Shewanella putrefaciens-Mineral-U” System
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Article
MiR-92 overexpression suppresses immune cell function in ovarian cancer via LATS2/YAP1/PD-L1 pathway
Increasing evidence suggested that microRNA plays an important role in ovarian cancer. In this study, the role of miR-92 in ovarian cancer was investigated.
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Article
Non-invasive and real-time proliferative activity estimation based on a quantitative radiomics approach for patients with acromegaly: a multicenter study
Proliferative activity prediction is important for determining individual treatment strategies for patients with acromegaly, and tumor proliferative activity is usually measured by the expression of Ki-67.
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Article
Open AccessVaporization of Ni, Al and Cr in Ni-Base Alloys and Its Influence on Surface Defect Formation During Manufacturing of Single-Crystal Components
Vaporization and its associated surface defect formation have become one of the most important challenges in manufacturing single-crystal components. During the kinetic-influenced casting and solution heat tre...
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Article
Resonant peak splitting in finite periodic superlattices with an unit cell of two barriers and two wells on monolayer graphene
The general expressions for transmission probability and resonant peaks in one-dimensional N-periods graphene superlattice with unit cell of two barriers and two wells are analytically derived, and two types o...
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Article
(Im)mobilization of soil heavy metals using CaO, FA, sulfur, and Na2S: a 1-year incubation study
The immobilization of heavy metals (HMs)-contaminated soils using amendments is a cost-effective remediation technique. Therefore, the aim of this study was to evaluate the effectiveness and aging factor of C...
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Article
Characterization and Crystal Structure of a Novel Mononuclear Cobalt(II) Complex with Hydrazone Derived from Protocatechuic Acid
A novel complex [CoII(L)2·CH3OH] with hydrazone derived from protocatechuic acid (HL=C16H14N2O4) is designed and synthesized. The complex is characterized by single crystal X-ray diffraction, elemental analysis, ...
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Article
Open AccessEfficacy and safety of carfilzomib regimens in multiple myeloma patients relapsing after autologous stem cell transplant: ASPIRE and ENDEAVOR outcomes
Autologous stem cell transplantation (ASCT) is a standard treatment for eligible multiple myeloma (MM) patients, but many patients will relapse after ASCT and require subsequent therapy. The proteasome inhibit...
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Article
Open AccessCarfilzomib–dexamethasone vs bortezomib–dexamethasone in relapsed or refractory multiple myeloma by cytogenetic risk in the phase 3 study ENDEAVOR
The randomized phase 3 study ENDEAVOR demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) for carfilzomib and dexamethasone (Kd) vs bortezomib and ...
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Article
Identification and expression analysis of seven MADS-box genes from Annona squamosa
MADS-box genes encode a family of transcription factors that regulate diverse growth and developmental processes in plants, including flowering. In this study, comprehensive characterization and expression pro...
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Article
Open AccessImpact of prior treatment on patients with relapsed multiple myeloma treated with carfilzomib and dexamethasone vs bortezomib and dexamethasone in the phase 3 ENDEAVOR study
The randomized phase 3 ENDEAVOR study (N=929) compared carfilzomib and dexamethasone (Kd) with bortezomib and dexamethasone (Vd) in relapsed multiple myeloma (RMM). We performed a subgroup analysis from ENDEAVOR ...
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Article
Identification of transcription factors (TFs) and targets involved in the cholangiocarcinoma (CCA) by integrated analysis
The present study was designed to investigate the upstream transcription factors (TFs) and the signature genes in cholangiocarcinoma (CCA), providing better clues on the regulatory mechanisms and therapeutic a...
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Article
CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation
Melanoma is one of the most lethal forms of skin cancer because of its early metastatic spread. The variant form of CD44 (CD44v), a cell surface glycoprotein, is highly expressed on metastatic melanoma. The me...
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Article
Efficacy and safety of catheter ablation vs. rate control of atrial fibrillation in systolic left ventricular dysfunction
It is unclear what constitutes the optimal strategy for management of atrial fibrillation (AF) in patients with systolic left ventricular (LV) dysfunction. We hypothesized that catheter ablation of AF had bene...
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Article
Open AccessThe change of a district hospital antimicrobial consumption in and after national antimicrobial appropriate use intervention, China
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Article
Open AccessHall and field-effect mobilities in few layered p-WSe2 field-effect transistors
Here, we present a temperature (T) dependent comparison between field-effect and Hall mobilities in field-effect transistors based on few-layered WSe2 exfoliated onto SiO2. Without dielectric engineering and beyo...
