17 Result(s)
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Article
Open AccessCase report: when two and ½ men go cam**…
In patients, rapid identification of bacterial species may help to guide treatment at early stages. New protocols for the identification directly from positive blood culture flasks significantly helped in the ...
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Open AccessAntibiotic resistance in Swiss nursing homes: analysis of National Surveillance Data over an 11-year period between 2007 and 2017
We evaluated data from isolates of nursing home (NH) patients sent to the Swiss centre for antibiotic resistance (ANRESIS). We focussed on carbapenem-resistance (CR) among Gram-negative pathogens, extended-spe...
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Article
Open AccessClinical impact of the type VI secretion system on virulence of Campylobacter species during infection
The clinical course of Campylobacter infection varies in symptoms and severity depending on host factors, virulence of the pathogen and initiated therapy. The type VI secretion system (T6SS) has been identified a...
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Open AccessProsthetic valve endocarditis caused by Pseudomonas aeruginosa with variable antibacterial resistance profiles: a diagnostic challenge
Infective endocarditis (IE) caused by gram-negative bacilli is rare. However, the incidence of this severe infection is rising because of the increasing number of persons at risk, such as patients with immunos...
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Open AccessAgrobacterium spp. nosocomial outbreak assessment using rapid MALDI-TOF MS based ty**, confirmed by whole genome sequencing
A number of episodes of nosocomial Agrobacterium spp. bacteremia (two cases per year) were observed at Bern University Hospital, Switzerland, from 2015 to 2017. This triggered an outbreak investigation.
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Open AccessPredictors of infectious meningitis or encephalitis: the yield of cerebrospinal fluid in a cross-sectional study
Cerebrospinal fluid (CSF) analyses are recommended in patients with meningitis and/or encephalitis, but evidence regarding its diagnostic yield is low. We aimed to determine predictors of infectious pathogens ...
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Open AccessAccuracy of urine flow cytometry and urine test strip in predicting relevant bacteriuria in different patient populations
Urinary tract infection (UTI) is diagnosed combining urinary symptoms with demonstration of urine culture growth above a given threshold. Our aim was to compare the diagnostic accuracy of Urine Flow Cytometry ...
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Open AccessBilateral acute renal cortical necrosis after a dog bite: case report
Capnocytophaga canimorsus is a Gram-negative capnophilic rod and part of dogs/cats’ normal oral flora. It can be transmitted by bites, scratches, or even by contact of saliva with injured skin. Asplenic patients ...
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Open AccessSystematic screening on admission for SARS-CoV-2 to detect asymptomatic infections
The proportion of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains elusive and the potential benefit of systematic screening during the SARS-CoV-2-pandemic is contr...
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Open AccessRisk factors for colonization with multiple species of extended-spectrum beta-lactamase producing Enterobacterales: a case-case–control study
Approximately 11% of patients colonized with extended-spectrum beta-lactamase producing Enterobacterales (ESBL-PE) are colonized with more than one ESBL-producing species. We investigated risk factors associat...
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Article
Open AccessAgrobacterium species bacteraemia, Switzerland, 2008 to 2019: a molecular epidemiological study
Agrobacterium spp. are infrequent agents of bloodstream infections linked to healthcare-associated outbreaks. However, it is unclear if outbreaks also occur across larger geographic areas. Triggered by two local ...
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Open AccessPatients exposed to vancomycin-resistant enterococci during in-hospital outbreaks in a low endemic setting: a proposal for risk-based screening
The optimal extent of screening of contact patients (CoPat) after exposure to patients infected or colonized with vancomycin-resistant enterococci (VRE) remains controversial.
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Open AccessA systematic outbreak investigation of SARS-CoV-2 transmission clusters in a tertiary academic care center
We sought to decipher transmission pathways in healthcare-associated infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within our hospital by epidemiological work-up and complementar...
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Open AccessLegionnaires’ disease in Switzerland: rationale and study protocol of a prospective national case–control and molecular source attribution study (SwissLEGIO)
Switzerland has one of the highest annual Legionnaires’ disease (LD) notification rates in Europe (7.8 cases/100,000 population in 2021). The main sources of infection and the cause for this high rate remain l...
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Open AccessIdentification of microorganisms by a rapid PCR panel from positive blood cultures leads to faster optimal antimicrobial therapy – a before-after study
The BioFire® FilmArray® Blood Culture Identification Panel 1 (BF-FA-BCIP) detects microorganisms with high accuracy in positive blood cultures (BC) – a key step in the management of patients with suspected bac...
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Open AccessEvaluation of the clinical relevance of the Biofire© FilmArray pneumonia panel among hospitalized patients
Panel PCR tests provide rapid pathogen identification. However, their diagnostic performance is unclear. We assessed the performance of the Biofire© FilmArray pneumonia (PN)-panel against standard culture in bron...
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Open AccessTularemia on the rise in Switzerland? A one health approach is needed!
In the last 10 years, an increase in tularemia cases has been observed in both humans and animals in Switzerland. In these, infection with Francisella tularensis, the causative agent of the zoonotic disease tular...
