1,110 Result(s)
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Life Sciences
Chemistry/Food Science, general
Organic Chemistry
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Article
Plant cell factories as a source for anti-cancer lignans
The review places podophyllotoxin, a powerful anti-cancer material used in clinical treatment of small cell cancers, in focus. The economical synthesis of podophyllotoxin is not feasible and demand for this ma...
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Antibody molecular farming in plants and plant cells
`Molecular Farming' is a novel approach to the production of pharmaceuticals, where valuable recombinant proteins can be produced in transgenic organisms on an agricultural scale. Plants have been traditionall...
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Biotechnology and the improvement of oil crops – genes, dreams and realities
During the past decade, there have been many optimistic claims concerning the potential of novel oil-based products from genetically engineered crops, particularly for the manufacture of a new generation of re...
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Polymers of 3-hydroxyacids in plants
Polyhydroxyalkanoates (PHA) are polyesters of bacterial origin that have properties of biodegradable plastics and elastomers. Synthesis of PHA in crop plants would allow the large-scale production and use of t...
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The challenges facing scientists in the development of foods in Europe using biotechnology
The public's major concern over the introduction of genetic engineering into the food chain focuses on potential health risks. Proving that a food is safe is an impossible goal since there will always be a ris...
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Future prospects for transgenic crops
Transgenic (genetically modified) crops are grown at present on more than 40 million hectares in 13 countries around the world. These `first generation' products principally comprise soybean, maize (corn) and ...
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Metabolic engineering of a complex biochemical pathway: The lysine and threonine biosynthesis as an example
The nutritional quality of crop plants is determined by their content in essential amino acids provided in food for humans or in feed for monogastric animals. Amino acid composition of crop–based diets can be ...
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Pharming vaccines for hepatitis and cytomegalovirus: Towards the development of multivalent and subunit vaccines for oral delivery of antigens
A plant based high fidelity vaccine production system is being developed with emphasis on producing antigens capable of being orally delivered in multivalent or subunit plant packets. Plant-based edible vaccin...
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Technical enzymes produced in transgenic plants
Technical enzymes are used in many industrial applications. Nowadays technical enzymes are often produced in transgenic host organisms. The use of transgenic plants with respect to high level of expression at ...
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Improving the nutritional content of tomatoes through reprogramming their flavonoid biosynthetic pathway
Flavonoids are a diverse group of phenolic secondary metabolites that occur naturally in plants and therefore form an integral component of the human diet. Many of the compounds belonging to this group are pot...
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Biotechnology for the production of plant secondary metabolites
The production of plant secondary metabolites by means of large-scale culture of plant cells in bioreactors is technically feasible. The economy of such a production is the major bottleneck. For some costly pr...
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Characterization of microstructure and cell wall components of Arabidopsis thaliana overexpressing cyclin-dependent kinase inhibitor 2
Overexpression of a cyclin-dependent kinase inhibitor (KRP2) caused changes in the general morphology in the leaves of Arabidopsis thaliana. The wild type plant had obovate leaves with entire margins whereas the ...
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Aspects of cytotoxic lignan biosynthesis in suspension cultures of Linum nodiflorum
Plant cell suspension cultures of Linum flavum, Linum nodiflorum and Linum album have been used to characterize the growth and production of cytotoxic lignans as well as to study the biosynthesis of these lignans...
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Improvement of malting quality of barley by complementing the malt enzyme spectrum
The processing quality of cereals can be modified by altering the structural grain constituents or the enzyme activities that mobilize storage reserves of the seeds. In order to complement the malt enzyme spec...
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Food insecurity: Prevalence, causes, and the potential of transgenic `Golden Rice'
This paper reviews a number of recent social science publications on the nature and causes of food insecurity in low and middle-income countries. The focus is on one specific element of food insecurity, vitami...
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The use of flavonoid aglycones in in vitro systems to test biological activities: based on bioavailability data, is this a valid approach?
The majority of in vitro assays on biological activities of flavonoids have used the aglycone form as the test compound. This form is readily available from commercial sources and comparable approaches have been ...
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Cocoa flavanols and cardiovascular health
Fruits and vegetables have historically been considered rich sources of essential dietary micronutrients, soluble fiber, and antioxidants. More recently they are have been recognized as important sources for a...
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Bioinformatics and Computational Biology at the crossroads of post-genomic technology
The traditional approach of experimental biology is strongly based on the analysis of the individual components, genes and proteins. In this case bioinformatics methods are essential for the organization of th...
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Can metabolomics be used for assessing nutritive-dependent human diseases?
Metabolomic approaches are taking place within emerging technologies that share the focus to unravel unexpected effects in classical biological experiments, for example mutant/wild type comparisons. This revie...
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Metabolism of isoflavones in human subjects
Isoflavones form a group of plant compounds that occur mainly in legumes, soy being the most important source in human diet. The high levels of isoflavones in the diet have been associated with a lowered risk ...
