209 Result(s)
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Life Sciences
Chemistry/Food Science, general
Organic Chemistry
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Pharming vaccines for hepatitis and cytomegalovirus: Towards the development of multivalent and subunit vaccines for oral delivery of antigens
A plant based high fidelity vaccine production system is being developed with emphasis on producing antigens capable of being orally delivered in multivalent or subunit plant packets. Plant-based edible vaccin...
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Open AccessHot Cuisine as a Source of Anti-Inflammatory Drugs
The shift in nutritional sciences from survival and safety to the promotion of well-being has led to systematic investigations on the biological activity of natural products of dietary origin, questioning the ...
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Open AccessPlant Derived Antimalarial Agents: New Leads and Challenges
New treatments for malaria are urgently needed due to the increasing problem of drug-resistance in malaria parasites. The long-established use of quinine and the more recent introduction of artemisinin and its...
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Open AccessCannabinoids in Models of Chronic Inflammatory Conditions
Cannabis sativa has been used as an anti-inflammatory plant for millennia. However until the elucidation of the chemistry of its constituents and the discovery of the endogenous cannabinoid system only a limit...
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Open AccessBiological Activities and Chemistry of Saponins from Panax ginseng C. A. Meyer
The roots of Panax ginseng C. A. Meyer, known as Korean ginseng have been a valuable and important folk medicine in the East Asian countries, such as China, Korea and Japan for about 2000 years. Panax is derived ...
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Open AccessMetabolic Engineering of Terpenoid Biosynthesis in Plants
Metabolic engineering of terpenoids in plants is a fascinating research topic from two main perspectives. On the one hand, the various biological activities of these compounds make their engineering a new tool...
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Open AccessArabidopsis cytochrome P450s through the looking glass: a window on plant biochemistry
Annotation of the genome sequence of Arabidopsis thaliana has identified a diverse array of 245 full-length cytochrome P450 monooxygenase (P450) genes whose known functions span the synthetic gamut from critical ...
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Open AccessPlant cytochrome P450s from moss to poplar
This review represents the first attempt to define the origins of the major P450-containing pathways in plants. Comparative genomics with five complete P450 gene sets from Chlamydomonas reinhardtii with 39 sequen...
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Open AccessNMR-based metabolomics at work in phytochemistry
Metabolomics is defined as both the qualitative and quantitative analysis of all metabolites in an organism unraveling correlation with other OMICs data. Many of the technologies used in metabolomics have meth...
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Dedication
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Open AccessTranscription factors involved in terpenoid indole alkaloid biosynthesis in Catharanthus roseus
Plants produce alkaloids, among others, to protect themselves against microbial infection, herbivore attack or ultraviolet irradiation. For man, alkaloid metabolism is the source of many natural products with ...
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Open AccessPhenolic compounds in Catharanthus roseus
Besides alkaloids Catharanthus roseus produces a wide spectrum of phenolic compounds, this includes C6C1 compounds such as 2,3-dihydoxybenzoic acid, as well as phenylpropanoids such as cinnamic acid derivatives, ...
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Open AccessRole of vacuolar transporter proteins in plant secondary metabolism: Catharanthus roseus cell culture
Here the current status of knowledge on some well-characterized transporters located in the vacuolar membrane is reviewed. As different cellular compartments and even different cells may be involved in certain...
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Open AccessCatharanthus terpenoid indole alkaloids: biosynthesis and regulation
Catharanthus roseus is still the only source for the powerful antitumour drugs vinblastine and vincristine. Some other pharmaceutical compounds from this plant, ajmalicine and serpentine ...
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Cyanogenic glycosides: a case study for evolution and application of cytochromes P450
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Open AccessSecondary transport as an efficient membrane transport mechanism for plant secondary metabolites
Plants produce a large number of secondary metabolites, such as alkaloids, terpenoids, and phenolic compounds. Secondary metabolites have various functions including protection against pathogens and UV light i...
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Transgenic plants for animal health: plant-made vaccine antigens for animal infectious disease control
A variety of plant species have been genetically modified to accumulate vaccine antigens for human and animal health and the first vaccine candidates are approaching the market. The regulatory burden for anima...
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Open AccessPhytochemistry reviews—special issue on glucosinolates
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Open AccessA robust omics-based approach for the identification of glucosinolate biosynthetic genes
Transcriptome coexpression analysis, which is based on a vast amount of transcriptome data obtained by using DNA arrays, has become a routine method for functional genomics studies in Arabidopsis. This analysis e...
