7 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
**-hua Leng
Article
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Article
Humification degrees of peat in Qinghai-**zang Plateau and palaeoclimate change
In this article we report a new and sensitive palaeoclimate proxy indicator-humification degrees of peat. Based on the comparison of humification degrees with other climate proxy records, such as λ13C time series...
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Article
Open AccessDoxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2
Chemotherapies often induce drug-resistance in cancer cells and simultaneously stimulate proliferation and activation of Myeloid-Derived Suppressor Cells (MDSCs) to inhibit anti-tumor T cells, thus result in p...
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Article
Open AccessIntestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect
TGR5 activation of enteroendocrine cells increases glucagon-like peptide 1 (GLP-1) release, which maintains glycemic homeostasis. However, TGR5 activation in the gallbladder and heart is associated with severe...
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Article
Open AccessCyclooxygenase-2 induced β1-integrin expression in NSCLC and promoted cell invasion via the EP1/MAPK/E2F-1/FoxC2 signal pathway
Cyclooxygenase-2 (COX-2) has been implicated in cell invasion in non-small-cell lung cancer (NSCLC). However, the mechanism is unclear. The present study investigated the effect of COX-2 on β1-integrin express...
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Article
Open AccessControllable deuteration of halogenated compounds by photocatalytic D2O splitting
Deuterium labeling is of great value in organic synthesis and the pharmaceutical industry. However, the state-of-the-art C–H/C–D exchange using noble metal catalysts or strong bases/acids suffers from poor fun...
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Article
Open AccessTuneable near white-emissive two-dimensional covalent organic frameworks
Most two-dimensional (2D) covalent organic frameworks (COFs) are non-fluorescent in the solid state even when they are constructed from emissive building blocks. The fluorescence quenching is usually attribute...
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Article
Open AccessRegio- and enantioselective umpolung gem-difluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand
The enantioselective construction of C–CF2R (R: alkyl or fluoroalkyl) bonds has attracted the attention of synthetic chemists because of the importance of chiral fluorinated compounds in life and materials scienc...
