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Article
Multiple Perspectives of Study on the Potential of Bacillus amyloliquefaciens JB20221020 for Alleviating Nutrient Stress in Lettuce
Soil nutrient deficiency has become a key factor limiting crop growth. Plant growth-promoting rhizobacteria (PGPR) are vital in resisting abiotic stress. In this study, we investigated the effects of inoculati...
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Article
Open AccessChemotherapy resistance in acute myeloid leukemia is associated with decreased anti-tumor immune response through MHC molecule and B7 family members
Acute myeloid leukemia (AML) remains challenging due to chemotherapeutic drug-resistance (CDR). Aberrant expression B7 family proteins are involved in tumors evasion. We wonder whether B7 family protein altera...
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Article
Construction of a Membrane Yeast Two-Hybrid Library and Screening of MsPYR1-Like Interacting Proteins in Malus sieversii
To investigate the biological effects of the ABA receptor pyrabactin resistance 1-like (PYR1-like) in Malus sieversii seeds, the proteins interacting with MsPYR1-like were screened by the membrane yeast two-hybri...
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Article
Research on surface integrity of TC4 titanium alloy by ultrasonic surface rolling peening
In order to investigate the effects of different spindle speeds on the surface integrity of TC4 specimens and the effect of ultrasonic-assisted rolling strengthening on the enhancement of microstructure and me...
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Article
Open AccessUsing multi-omics to explore the effect of Bacillus velezensis SAAS-63 on resisting nutrient stress in lettuce
To avoid the unreasonable use of chemical fertilizer, an environmentally friendly means of improving soil fertility is required. This study explored the role of the plant growth-promoting rhizosphere bacteria ...
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Article
Open AccessPredictive effect of triglyceride-glucose index on No-Reflow Phenomenon in patients with type 2 diabetes mellitus and acute myocardial infarction undergoing primary percutaneous coronary intervention
Triglyceride glucose (TyG) index is considered as a new alternative marker of insulin resistance and a clinical predictor of type 2 diabetes mellitus (T2DM) combined with coronary artery disease. However, the ...
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Article
Open AccessUnderstanding immune microenvironment alterations in the brain to improve the diagnosis and treatment of diverse brain diseases
Abnormal inflammatory states in the brain are associated with a variety of brain diseases. The dynamic changes in the number and function of immune cells in cerebrospinal fluid (CSF) are advantageous for the e...
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Article
Open AccessPolystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism
Nanoplastics (NPs) are omnipresent in our lives as a new type of pollution with a tiny size. It can enter organisms from the environment, accumulate in the body, and be passed down the food chain. Inflammatory...
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Article
Open AccessSoft ferroelectret ultrasound receiver for targeted peripheral neuromodulation
Bioelectronic medicine is a rapidly growing field where targeted electrical signals can act as an adjunct or alternative to drugs to treat neurological disorders and diseases via stimulating the peripheral ner...
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Article
InSAR-based landslide detection method with the assistance of C-index
Interferometric Synthetic Aperture Radar (InSAR) has been increasingly used in landslide detection over wide areas. However, atmospheric delays, phase unwrap** errors, and noise, which behave like deformatio...
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Article
A new radial basis function active learning method based on distance constraint for structural reliability analysis
Strongly nonlinear structural systems exhibit high computational errors when dependability is calculated using conventional approaches such as the primary second-order method of moments and the secondary secon...
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Article
A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants
Multivalent vaccines combining crucial mutations from phylogenetically divergent variants could be an effective approach to defend against existing and future SARS-CoV-2 variants. In this study, we developed a...
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Article
Some selected topics on structural safety
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Article
Bispecific anti-CD3×anti-CD155 antibody mediates T-cell immunotherapy in human haematologic malignancies
T cells are important components in the cell-mediated antitumour response. In recent years, bispecific antibodies (Bi-Abs) have become promising treatments because of their ability to recruit T cells that kill...
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Article
Open AccessDeep vein thrombosis in a patient with Cronkhite-Canada syndrome: a complex case report
Cronkhite-Canada syndrome (CCS) is a rare disease characterized by generalized gastrointestinal polyps, ectodermal abnormalities and variable gastrointestinal symptoms. Few cases to date have described complic...
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Article
Open AccessA retrospective cohort study of tamoxifen versus surgical treatment for ER-positive gynecomastia
Gynecomastia is a common condition in clinical practice. The present study aimed to review the clinical data of ER-positive gynecomastia patients treated by tamoxifen (TAM) versus surgery and discussed the cli...
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Article
Influence of High Rotational Speeds on the Microstructure and Properties of Friction Stir Manufactured ZK61 Magnesium Alloy-Hydroxyapatite Composites
Friction stir processing (FSP) with high rotational speeds was successfully adopted to fabricate nano-hydroxyapatite (nHA)-reinforced ZK61 magnesium matrix composites (MMCs). And the influence of high rotation...
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Article
The neuropeptide CGRP enters the macrophage cytosol to suppress the NLRP3 inflammasome during pulmonary infection
The NLRP3 inflammasome plays an essential role in resistance to bacterial infection. The nervous system secretes multiple neuropeptides affecting the nervous system as well as immune cells. The precise impact ...
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Article
Open AccessSafety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects
VV116 (JT001) is an oral drug candidate of nucleoside analog against SARS-CoV-2. The purpose of the three phase I studies was to evaluate the safety, tolerability, and pharmacokinetics of single and multiple a...
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Article
Simulation and experimental study on width and depth of melting pool in laser polishing Ti-6Al-4V alloy
The variation of melting width and depth with laser power and scanning speed was investigated experimentally to study the melting pool’s influence law during lase polishing Ti-6Al-4V alloy. A three-dimensional...
