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Article
Open AccessEpidemiological and clinical profile of pediatric hepatitis B virus infections in Wuhan: a retrospective cohort study
Hepatitis B virus (HBV) remains a substantial public health safety concern drawing considerable attention in China and globally. The detection of HBV serological markers can enable the assessment of HBV infect...
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Article
4-HNE Induces Apoptosis of Human Retinal Pigment Epithelial Cells by Modifying HSP70
The role of heat shock protein 70 (HSP70) in apoptosis of human retinal pigment epithelial cells (ARPE-19) induced by 4-hydroxy-2-nonenal (4-HNE) was explored. Different concentrations of 4-HNE were used to st...
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Article
Open AccessPrognostic significance of K-ras mutations in pancreatic cancer: a meta-analysis
K-ras gene mutations are common in patients with pancreatic cancer (PC); however, their prognostic value for PC remains inconclusive. This meta-analysis was performed to quantitatively evaluate the association...
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Article
Open AccessDoxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2
Chemotherapies often induce drug-resistance in cancer cells and simultaneously stimulate proliferation and activation of Myeloid-Derived Suppressor Cells (MDSCs) to inhibit anti-tumor T cells, thus result in p...