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Open AccessCooperative coevolutionary surrogate ensemble-assisted differential evolution with efficient dual differential grou** for large-scale expensive optimization problems
This paper proposes a novel algorithm named surrogate ensemble assisted differential evolution with efficient dual differential grou** (SEADECC-EDDG) to deal with large-scale expensive optimization problems ...
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Article
Open AccessEffect mechanism investigation of herb-partitioned moxibustion on relieving colon inflammation in Crohn disease rats based on neutrophil extracellular traps
To explore the mechanism of herb-partitioned moxibustion in relieving rat intestinal inflammation by focusing on the neutrophil extracellular traps (NETs) in Crohn disease (CD) development.
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Article
Open AccessA novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
Severe sharp angular kyphosis resulting from Pott’s disease typically necessitates surgical intervention. The deployment of three-column osteotomy within the lesion and apical regions has been validated as an ...
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Article
Open AccessSurrogate Ensemble-Assisted Hyper-Heuristic Algorithm for Expensive Optimization Problems
This paper proposes a novel surrogate ensemble-assisted hyper-heuristic algorithm (SEA-HHA) to solve expensive optimization problems (EOPs). A representative HHA consists of two parts: the low-level and the hi...
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Article
Open AccessTyrosine phosphorylation of band 3 impairs the storage quality of suspended red blood cells in the Tibetan high-altitude polycythemia population
Due to environmental hypoxia on the Tibetan Plateau, local residents often exhibit a compensative increase in hemoglobin concentration to maintain the body’s oxygen supply. However, increases in hemoglobin and...
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Open AccessPulmonary and clinical outcomes of patients with severe rigid scoliosis and type I respiratory failure treated with halo-pelvic distraction
The severe rigid scoliosis patients with type I respiratory failure could not tolerate complicated corrective surgery. Preoperative halo-pelvic distraction (HPD) is used to reduce the curve magnitude and impro...
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Article
Open AccessSerum liver fibrosis markers predict hepatic decompensation in compensated cirrhosis
The literature is sparse on the association between serum liver fibrosis markers and the development of hepatic decompensation in patients with compensated cirrhosis. We aimed to assessed whether the serum liv...
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Article
Open AccessSelf-anticoagulant sponge for whole blood auto-transfusion and its mechanism of coagulation factor inactivation
Clinical use of intraoperative auto-transfusion requires the removal of platelets and plasma proteins due to pump-based suction and water-soluble anticoagulant administration, which causes dilutional coagulopa...
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Article
Open AccessCooperative coevolutionary differential evolution with linkage measurement minimization for large-scale optimization problems in noisy environments
Many optimization problems suffer from noise, and the noise combined with the large-scale attributes makes the problem complexity explode. Cooperative coevolution (CC) based on divide and conquer decomposes th...
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Article
Open AccessRandomized controlled trials of acupuncture for the treatment of essential hypertension: a meta-analysis
To systematically assess the efficacy and safety of acupuncture therapy for essential hypertension.
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Article
Open AccessStaged osteotomy in lateral position for the treatment of severe kyphotic deformity secondary to ankylosing spondylitis: a retrospective study
Patients with severe kyphotic deformity (Cobb > 100°) secondary to ankylosing spondylitis (AS) occasionally cannot undergo corrective surgery in the prone position. Osteotomy in the lateral position might prov...
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Article
Open AccessWearable synthetic leather-based high-performance X-ray shielding materials enabled by the plant polyphenol- and hierarchical structure-facilitated dispersion
Effective protection against X-ray is the premise of utilizing the X-ray, thus it is critical to develop novel X-ray shielding materials with both low density and high X-ray attenuation efficiency. As the even...
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Open AccessEffects of family multi-generational relationship on multimorbidity and healthy life expectancy for second generations: insight from the China Health and Retirement Longitudinal Study
In the context of aging, Chinese families consisting of more than three generations (grandparents, parents, children) are the norm. The second generation (parents) and other family members may establish a down...
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Article
Open AccessToward the recognition of spacecraft feature components: A new benchmark and a new model
Countries are increasingly interested in spacecraft surveillance and recognition which play an important role in on-orbit maintenance, space docking, and other applications. Traditional detection methods, incl...
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Article
Open AccessEffects of insomnia and levels of depression and anxiety symptoms on quality of life in people with epilepsy
The association between insomnia and quality of life (QOL) in epilepsy is poorly understood and may involve interactive variables. We aimed to investigate whether and how insomnia, levels of depression and anx...
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Article
Open AccessSocial support for and features of Chinese adults with epilepsy
The lack of social support for adults with epilepsy (AWEs) is receiving increased attention, as it may result in low quality of life. This study was aimed to confirm the demographic characteristics of and clin...
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Article
Open AccessClinical and genomic features of Chinese lung cancer patients with germline mutations
The germline mutation landscape in Chinese lung cancer patients has not been well defined. In this study, sequencing data of 1,021 cancer genes of 1,794 Chinese lung cancer patients was analyzed. A total of 11...
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Article
Open AccessSerum ferritin levels are associated with advanced liver fibrosis in treatment-naive autoimmune hepatitis
The association between iron-metabolism-related variables and liver fibrosis in chronic hepatitis C and nonalcoholic fatty liver disease is now well known. However, the relationship has not been extensively st...
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Open AccessmiR-539 activates the SAPK/JNK signaling pathway to promote ferropotosis in colorectal cancer by directly targeting TIPE
Colorectal cancer (CRC) is a common tumor that harms human health with a high recurrence rate. It has been reported that the expression of microRNA-539 (miR-539) is low in several types of cancer, including CR...
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Open AccessProtein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice
The pathogenic mechanisms underlying the development of Alzheimer’s disease (AD) remain elusive and to date there are no effective prevention or treatment for AD. Farnesyltransferase (FT) catalyzes a key postt...
