Skip to main content

19,368 Result(s)

within Jian** ** Remove this filter Science, multidisciplinary Remove this filter

Page of 969
and

  1. Article

    Phototactic purple bacteria

    Lisa Ragatz, Ze-Yu Jiang, Carl Bauer, Howard Gest in Nature (1994)

    Download PDF (1789 KB)

  2. No Access

    Article

    An early haematopoietic defect in mice lacking the transcription factor GATA-2

    Blood cell development relies on the expansion and maintenance of haematopoietic stem and progenitor cells in the embryo. By gene targeting in mouse embryonic stem cells, we demonstrate that the transcription ...

    Fong-Ying Tsai, Gordon Keller, Frank C. Kuo, Mitchell Weiss, Jianzhou Chen… in Nature (1994)

  3. No Access

    Article

    Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

    THE protease inhibitor α,-antichymotrypsin and the lipid transport protein apolipoprotein E (apoE) are intimately associated with the 42-amino-acid β-peptide (Aβ) in the filamentous amyloid deposits of Alzheim...

    Jianyi Ma, Ann Yee, H. Bryan Brewer Jr, Saumya Das, Huntington Potter in Nature (1994)

  4. No Access

    Article

    Ypt1p implicated in v-SNARE activation

    SYNAPTOBREVIN-LIKE membrane proteins that reside on transport vesicles, called the vesicle SNARE (v-SNARE), play a key role in ensuring that a vesicle targets and fuses with its correct acceptor compartment1–3. H...

    Jian P. Lian, Shelly Stone, Yu Jiang, Patrick Lyons, Susan Ferro-Novick in Nature (1994)

  5. No Access

    Article

    Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA

    LACTOFERRIN, an iron-binding glycoprotein found in high concentrations in human milk and other epithelial secretions1 and in the secondary (specific) granules of neutrophils2, is thought to be responsible for pri...

    Jianglin He, Philip Furmanski in Nature (1995)

  6. No Access

    Article

    A kinase–cyclin pair in the RNA polymerase II holoenzyme

    THE RNA polymerase II holoenzyme consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known as SRB proteins1,2. The genes encoding SRB proteins were isolated as suppre...

    Sha-Mei Liao, Jianhua Zhang, Douglas A. Jeffery, Anthony J. Koleske… in Nature (1995)

  7. No Access

    Article

    The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

    DENDRITIC cells and thymic epithelial cells perform important immunoregulatory functions by presenting antigens in the form of peptides bound to cell-surface major histocompatibility complex (MHC) molecules to...

    Wan** Jiang, William J. Swiggard, Christine Heufler, Michael Peng, Asra Mirza… in Nature (1995)

  8. No Access

    Article

    Interaction between the retinoblastoma protein and the oncoprotein MDM2

    INACTIVATION of tumour-suppressor genes leads to deregulated cell proliferation and is a key factor in human tumorigenesis. Both p53 and retinoblastoma genes are frequently mutated in human cancers1,2, and the si...

    Zhi-Xlong **ao, Jiandong Chen, Arnold J. Levine, Nazanlne Modjtahedi, Jun **ng… in Nature (1995)

  9. No Access

    Article

    Elevation of auditory thresholds by spontaneous cochlear oscillations

    THEinner ear sometimes acts as a robust sound generator, continuously broadcasting sounds (spontaneous otoacoustic emissions) which can be intense enough to be heard by other individuals standing nearby1–4. Parad...

    Nicholas L. Powers, Richard J. Salvi, Jian Wang, Vlasta Spongr, Chun **ao Qiu in Nature (1995)

  10. No Access

    Article

    Seismic anisotropy as an indicator of mantle flow beneath the Himalayas and Tibet

    SEVERAL models have been proposed for the geodynamical evolution of the Tibet–Himalayas collision zone1–6. It is now generally recognized that the high elevations of the region have been caused by mechanical thic...

    A. Hirn, M. Jiang, M. Sapin, J. Diaz, A. Nercessian, Q. T. Lu, J. C. Lépine… in Nature (1995)

  11. No Access

    Article

    Formation of 'bullets' by hydrodynamical instabilities in stellar outflows

    IMAGES of young stars1 and supernova remnants2 often reveal small, high-density knots of material which are interpreted as 'bullets' ejected by the source and propagating at supersonic speeds into the surrounding...

    James M. Stone, Jianjun Xu, Lee G. Mundy in Nature (1995)

  12. No Access

    Article

    A sex difference in the human brain and its relation to transsexuality

    TRANSSEXUALS have the strong feeling, often from childhood onwards, of having been born the wrong sex. The possible psycho-genie or biological aetiology of transsexuality has been the subject of debate for man...

    Jiang-Ning Zhou, Michel A. Hofman, Louis J. G. Gooren, Dick F. Swaab in Nature (1995)

  13. No Access

    Article

    Involvement of Ral GTPase in v-Src-induced phospholipase D activation

    AN early response to the tyrosine kinase activity of v-Src is an increase in phospholipase D (PLD) activity1, which leads to the generation of biologically active lipid second messengers, including phosphatidic a...

    Hong Jiang, **g-Qing Luo, Takeshi Urano, Paul Frankel, Zhimin Lu… in Nature (1995)

  14. No Access

    Article

    Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

    LACK of functional expression of CD40 ligand (CD40L) on T cells results in hyper-IgM syndrome (HIGMl), a human immunodeficiency associated with a severely impaired humoral immune response that is consistent wi...

    Iqbal S. Grewal, Jianchao Xu, Richard A. Flavell in Nature (1995)

  15. No Access

    Article

    Two mechanisms of quantized calcium release in skeletal muscle

    SKELETAL muscle uses voltage sensors in the transverse tubular membrane1–3 that are linked by protein–protein interactions4–6 to intracellular ryanodine receptors7–10, which gate the release of calcium from the s...

    M. G. Klein, H. Cheng, L. F. Santana, Y.-H. Jiang, W. J. Lederer, M. F. Schneider in Nature (1996)

  16. No Access

    Article

    Efficient integration of an intron RNA into double-stranded DNA by reverse splicing

    SOME group II introns are mobile elements as well as catalytic RNAs1,2. Introns aI1 and aI2 found in the gene COX1 in yeast mitochondria encode reverse transcriptases which promote site-specific insertion of the ...

    Jian Yang, Steven Zimmerly, Philip S. Perlman, Alan M. Lambowitz in Nature (1996)

  17. No Access

    Article

    Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

    THE retinoic acid-inducible transcription factor AP-2 is expressed in epithelial and neural crest cell lineages during murine development1–5. AP-2 can regulate neural and epithelial gene transcription, and is ass...

    Jian Zhang, Stephanie Hagopian-Donaldson, George Serbedzija, Jennifer Elsemore… in Nature (1996)

  18. No Access

    Article

    Using antibodies to perturb the coordination sphere of a transition metal complex

    METAL ions in the active sites of many metalloenzymes exhibit distinctive spectral and chemical features which are different from those of small inorganic complexes1,2. These features are the result of the unusu...

    Phalguni Ghosh, Doron Shabat, Sandeep Kumar, Subhash C. Sinha, Flavio Grynszpan… in Nature (1996)

  19. No Access

    Article

    Structural basis of RNA folding and recognition in an AMP–RNA aptamer complex

    THE catalytic properties of RNA1,2 and its well known role in gene expression and regulation are the consequence of its unique solution structures. Identification of the structural determinants of ligand recognit...

    Feng Jiang, R. Ajay Kumar, Roger A. Jones, Dinshaw J. Patel in Nature (1996)

  20. No Access

    Article

    Human homologues of yeast helicase

    Jian Lu, Janet R. Mullen, Steven J. Brill, Susanne Kleff, Annette M. Romeo… in Nature (1996)

Page of 969