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  1. No Access

    Article

    Synthesis and in vitro anticancer evaluation of 1,8-naphthalimide N(4) and S(4)-derivatives combining DNA intercalation and alkylation capabilities

    Research on DNA binding antitumor agents has been classically steered by either non-covalent (DNA intercalation) or covalent (DNA alkylation) interactions. In this context bi-functional anticancer molecules ar...

    Tamara Brider, Boris Redko, Mor Oron-Herman… in Research on Chemical Intermediates (2016)

  2. No Access

    Article

    1,4-Dihydropyridine Cationic Peptidomimetics with Antibacterial Activity

    We synthesized new broad spectrum antibacterial cationic peptidomimetics centered on a hydrophobic 1,4-dihydropyridine (1,4-DHP) scaffold. The synthesis involves the preparation of the scaffold in a three step...

    Inbal Lapidot, Amnon Albeck, Gary Gellerman… in International Journal of Peptide Research … (2015)

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    Article

    Using antibodies to perturb the coordination sphere of a transition metal complex

    METAL ions in the active sites of many metalloenzymes exhibit distinctive spectral and chemical features which are different from those of small inorganic complexes1,2. These features are the result of the unusu...

    Phalguni Ghosh, Doron Shabat, Sandeep Kumar, Subhash C. Sinha, Flavio Grynszpan… in Nature (1996)

  4. No Access

    Article

    Preparation, structure and stereodynamics of phosphorus-bridged calixarenes

    The pyrolysis of several dialkylphosphate ester derivatives of calix[4]arenes yielded the same phosphorus bridged compound7. Under the pyrolytic conditions the phosphate groups may be cleaved or intermolecularly ...

    Oleg Aleksiuk, Flavio Grynszpan… in Journal of inclusion phenomena and molecul… (1994)

  5. No Access

    Chapter

    Preparation, Structure and Stereodynamics of Phosphorus-Bridged Calixarenes

    The pyrolysis of several dialkylphosphate ester derivatives of calix[4]arenes yielded the same phosphorus bridged compound 7. Under the pyrolytic conditions the phosphate groups may be cleaved or intermolecularly...

    Oleg Aleksiuk, Flavio Grynszpan… in Calixarenes 50th Anniversary: Commemorativ… (1994)