31 Result(s)
within
Chong-**n Tian
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessQuantifying perinatal transmission of Hepatitis B viral quasispecies by tag linkage deep sequencing
Despite full immunoprophylaxis, mother-to-child transmission (MTCT) of Hepatitis B Virus still occurs in approximately 2–5% of HBsAg positive mothers. Little is known about the bottleneck of HBV transmission a...
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Open AccessCorrection: Corrigendum: Green tea consumption is associated with reduced incident CHD and improved CHD-related biomarkers in the Dongfeng-Tongji cohort
Scientific Reports 6: Article number: 24353; published online: 13 April 2016; updated: 31 May 2017. The original version of this Article contained errors in the order of the authors’ affiliations, and an addit...
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Open AccessIdentification of Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides
The current study explored the Na+/K+-ATPase (NKA) inhibition-independent proarrhythmic mechanisms of cardiac glycosides (CGs) which are well-known NKA inhibitors. With the cytosolic Ca2+ chelated by EGTA and BAP...
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Article
Open AccessPrognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors
Prognostic biomarkers for the pancreatic neuroendocrine tumors are needed. Proteomic study on insulinoma has been rarely reported. We identified the differential expression of proteins between insulinoma and t...
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Open AccessLong-term exposure to a ‘safe’ dose of bisphenol A reduced protein acetylation in adult rat testes
Bisphenol A (BPA), a typical environmental endocrine-disrupting chemical, induces epigenetic inheritance. Whether histone acetylation plays a role in these effects of BPA is largely unknown. Here, we investiga...
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Article
Open AccessMain Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders
Previous studies suggested patients with bipolar depressive disorder (BDd) or unipolar depressive disorder (UDd) have cerebral metabolites abnormalities. These abnormalities may stem from multiple sub-regions ...
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Open AccessGreen tea consumption is associated with reduced incident CHD and improved CHD-related biomarkers in the Dongfeng-Tongji cohort
Prospective studies on the association of green tea with risk of coronary heart disease (CHD) incidence were scarce. This study examined whether green tea can reduce CHD incidence and have a beneficial effect ...
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Open AccessOverweight, resting heart rate and prediabetes/diabetes: A population-based prospective cohort study among Inner Mongolians in China
We aimed to investigate the cumulative effect of overweight and resting heart rate on prediabetes/diabetes incidence in an 10-year follow-up study in Inner Mongolians. Among 1729 participants who were free fro...
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Article
Open AccessDemethylation of c-MYB binding site mediates upregulation of Bdnf IV in cocaine-conditioned place preference
Abnormal BDNF signaling contributes to the structural and behavioral plasticity induced by drugs of abuse. However, the mechanisms regulating expression of Bdnf in drug addiction remain elusive. In the present st...
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Article
Open AccessDynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation
Many infertile men are the victims of spermatogenesis disorder. However, conventional clinical test could not provide efficient information on the causes of spermatogenesis disorder and guide the doctor how to...
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Article
Open AccessDeactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety
The medial prefrontal cortex (mPFC) is implicated in processing sensory-discriminative and affective pain. Nonetheless, the underlying mechanisms are poorly understood. Here we demonstrate a role for excitator...
