8 Result(s)

Article

Author Correction: Single-cell analysis of develo** and azoospermia human testicles reveals central role of Sertoli cells

LiangYu Zhao, ChenCheng Yao, **aoYu **ng, Tao **g, Peng Li… in Nature Communications (2021)

Article

Single-cell analysis of develo** and azoospermia human testicles reveals central role of Sertoli cells

Clinical efficacy of treatments against non-obstructive azoospermia (NOA), which affects 1% of men, are currently limited by the incomplete understanding of NOA pathogenesis and normal spermatogenic microenvir...

LiangYu Zhao, ChenCheng Yao, **aoYu **ng, Tao **g, Peng Li… in Nature Communications (2020)

Article

Derivation and propagation of spermatogonial stem cells from human pluripotent cells

This study is designed to generate and propagate human spermatogonial stem cells (SSCs) derived from human pluripotent stem cells (hPSCs).

Huiming Xu, Mengbo Yang, Ruhui Tian, Yonghui Wang… in Stem Cell Research & Therapy (2020)

Article

Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation

Sertoli cells are the most important somatic cells contributing to the microenvironment (named niche) for spermatogonial stem cells (SSCs). They produce amounts of crucial growth factors and structure proteins...

Ruhui Tian, Chencheng Yao, Chao Yang, Zijue Zhu, Chong Li… in Stem Cell Research & Therapy (2019)

Article

Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b

The neurobehavioral effects of paternal smoking and nicotine use have not been widely reported. In the present study, nicotine exposure induced depression in the paternal generation, but reduced depression and...

**gbo Dai, Zhaoxia Wang, Wangjie Xu, Meixing Zhang, Zijue Zhu… in Scientific Reports (2017)

Article

Correction: Corrigendum: Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation

Scientific Reports 5: Article number: 16922; published online: 20 November 2015; updated: 21 February 2017. The export of human derived tissues and related materials from China is currently subject to regulato...

**gmei Hou, Minghui Niu, Linhong Liu, Zijue Zhu, … in Scientific Reports (2017)

Article

Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation

Many infertile men are the victims of spermatogenesis disorder. However, conventional clinical test could not provide efficient information on the causes of spermatogenesis disorder and guide the doctor how to...

Zijue Zhu, Chong Li, Shi Yang, Ruhui Tian, Junlong Wang… in Scientific Reports (2016)

Article

Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation

Spermatogonial stem cells (SSCs) have significant applications in both reproductive and regenerative medicine. However, primary human SSCs are very rare and a human SSC line has not yet been available. In this...

**gmei Hou, Minghui Niu, Linhong Liu, Zijue Zhu, … in Scientific Reports (2015)