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Article
Tolerance analysis and yield estimation using Monte Carlo simulation – case study on linear and nonlinear mechanical systems
Dimensions of individual components give rise to a critical dimension in an assembly, called the assembly dimension(s) or the assembly response(s). This concept is applicable to any engineering system. Thus, a...
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Article
Fabrication and mechanical characterization of glass fiber/Al2O3 hybrid-epoxy composite
This paper presents the development and mechanical characterization of hybrid composite consisting of glass fiber and aluminum oxide (Al2O3) particles reinforced with epoxy matrix. The hybrid Glass Fiber Reinforc...
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Article
Source rock properties and pore structural framework of the gas-prone Lower Permian shales in the Jharia basin, India
This paper examines the source rock potential and pore structural framework of Lower Permian shales belonging to Barren Measures and Barakar Formations of Jharia basin, eastern India. The Jharia basin contains...
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Article
Coal combustion analysis using Rock-Eval: importance of S4-Tpeak
The Rock-Eval technique has been conventionally used for source-rock analysis. In this work we document the importance of Rock-Eval S4 oxidation graphics and S4-Tpeak as indicators for coal reactivity and thermal...
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Article
Open AccessCell free DNA from respiratory pathogens is detectable in the blood plasma of Cystic Fibrosis patients
Diagnostically informative microbial cell-free DNA (cfDNA) can be detected from blood plasma during fulminant infections such as sepsis. However, the potential for DNA from airway pathogens to enter the circul...
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Article
Open AccessScreening potential plant species for arresting particulates in Jharia coalfield, India
Mining and related activities cause severe degradation of ambient air quality. A study of particulate matter (PM) across transportation, mining and control (C) sites for dust attenuation capacity (DAC) in sele...
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Article
Effect of number of blades in ducted turbine system on kinetic energy extraction from chimney flue gases – benchmarking with wind energy system
A multi-blade ducted wind turbine, also called the diffuser augmented wind turbine (DAWT) has a good wind energy conversion effect over the traditional wind turbine. The market potential for energy recovery fr...
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Article
Open AccessGenetic interaction involving photoperiod-responsive Hd1 promotes early flowering under long-day conditions in rice
Although flowering in rice has been extensively investigated, few studies focused on genetic interactions. Flowering evaluation of two recombinant inbred line (RIL) populations involving photo-insensitive rice...
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Article
Open AccessStructure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes
Proteasome inhibitors benefit patients with multiple myeloma and B cell-dependent autoimmune disorders but exert toxicity from inhibition of proteasomes in other cells. Toxicity should be minimized by reversib...
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Article
Numerical modelling-based pillar strength estimation for an increased height of extraction
Underground extraction of total thickness of a thick coal seam in single lift by bord and pillar method increases pillar height during retreat. Field studies found that the increase in pillar height affects th...
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Article
Kinetic Energy Recovery from the Chimney Flue Gases Using Ducted Turbine System
An innovative idea of extracting kinetic energy from man-made wind resources using ducted turbine system for on-site power generation is introduced in this paper. A horizontal axis ducted turbine is attached t...
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Article
Open AccessIn vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075
The nosocomial pathogen Acinetobacter baumannii is a frequent cause of hospital-acquired infections worldwide and is a challenge for treatment due to its evolved resistance to antibiotics, including carbapenems. ...
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Article
Open AccessImplantable amyloid hydrogels for promoting stem cell differentiation to neurons
We report a new class of amyloid-inspired peptide hydrogels that was designed and based on α-synuclein protein for which hydrogel formation is triggered by various stimuli, such as heating/cooling or changes i...
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Article
Open AccessEffect of curcumin analogs onα-synuclein aggregation and cytotoxicity
Alpha-synuclein (α-Syn) aggregation into oligomers and fibrils is associated with dopaminergic neuron loss occurring in Parkinson’s disease (PD) pathogenesis. Compounds that modulate α-Syn aggregation and inte...
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Article
Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange
Here, the authors describe genetically engineering the Pseudomonas genome by two-step allelic exchange. Suicide vector-encoded alleles are used to generate mutations by homologous recombination at the single base...
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Article
Open AccessEffect of Allelic Variation in Triticin on Bread- and Chapati-Making Qualities of Wheat (Triticum aestivum)
Triticin, a legumin-like storage protein of wheat endosperm, was discovered nearly three decades ago but so far there is no report on its effect on the processing quality of wheat that is thought to be determi...
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Article
Open AccessStructure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation
Mechanistic understanding of nucleation dependent polymerization by α-synuclein (α-Syn) into toxic oligomers and amyloids is important for the drug development against Parkinson's disease. However the structur...
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Article
An improved surface roughness prediction model using Box-Cox transformation with RSM in end milling of EN 353
In the present work, an attempt has been made to use Box-Cox transformation with response surface methodology to develop improve surface roughness prediction model in end milling of EN 353 steel using carbide ...
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Article
Prediction of Surface Roughness in Turning of EN 353 Using Response Surface Methodology
In the present work, an attempt has been made to investigate the influence of cutting speed, feed, depth of cut and nose radius on surface roughness during wet turning of EN 353 steel using tungsten carbide in...
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Article
Amyloid-Like Fibril Formation by Tachykinin Neuropeptides and Its Relevance to Amyloid β-Protein Aggregation and Toxicity
Protein aggregation and amyloid formation are associated with both pathological conditions in humans such as Alzheimer’s disease and native functions such as peptide hormone storage in the pituitary secretory ...