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    Article

    Effects of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor pravastatin on membrane lipids and membrane associated functions of Methanothermobacter thermautotrophicus

    The role of archaeal membrane and its lipid constituents was investigated in bioenergetic functions of Methanothermobacter thermautotrophicus. The effects were determined of the 3-hydroxy-3-methylglutaryl-coenzym...

    Z. Nováková, J. Blaško, I. Hapala, P. Šmigáň in Folia Microbiologica (2010)

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    Article

    Cytokine expression and signaling in drug-induced cellular senescence

    Cellular senescence guards against cancer and modulates aging; however, the underlying mechanisms remain poorly understood. Here, we show that genotoxic drugs capable of inducing premature senescence in normal...

    Z Novakova, S Hubackova, M Kosar, L Janderova-Rossmeislova, J Dobrovolna in Oncogene (2010)

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    Article

    Isolation and characterization of a N,N′-dicyclohexylcarbodiimide-resistant mutant of Methanothermobacter thermautotrophicus with alterations to the ATP synthesis machinery

    A spontaneous mutant of Methanothermobacter thermautotrophicus resistant toward the ATP-synthase inhibitor N,N′-dicyclohexylcarbodiimide (DCCD) was isolated. DCCD normally inhibits methanogenic electron-transport...

    Z. Nováková, A. I. Majerník, J. Bobáľová, M. Vidová, P. Šmigáň in Folia Microbiologica (2009)

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    Article

    Membrane proteins and squalene-hydrosqualene profile in methanoarchaeon Methanothermobacter thermautotrophicus resistant to N,N′-dicyclohexylcarbodiimide

    The biochemical basis of a defective bioenergetic system was attempted to be determined in N,N′-dicyclohexylcarbodiimide (DCCD)-resistant mutant of Methanothermobacter thermautotrophicus. Components participating...

    Z. Nováková, S. Šurín, J. Blaško, A. Majerník, P. Šmigáň in Folia Microbiologica (2008)

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    Article

    Oxygen- and carbon source-dependent transactivation effect of ABF1 on the expression of theAAC2 gene encoding mitochondrial ADP/ATP carrier

    M. Neboháčová, Z. Nováková, P. Haviernik, S. Betina, J. Kolarov in Folia Microbiologica (1996)