Skip to main content

7 Result(s)

within Yunje Cho Remove this filter Biological Microscopy Remove this filter

and

  1. No Access

    Article

    Constitutive activation mechanism of a class C GPCR

    Class C G-protein-coupled receptors (GPCRs) are activated through binding of agonists to the large extracellular domain (ECD) followed by rearrangement of the transmembrane domains (TMDs). GPR156, a class C or...

    **woo Shin, Junhyeon Park, Jieun Jeong… in Nature Structural & Molecular Biology (2024)

  2. No Access

    Article

    Eukaryotic Rad50 functions as a rod-shaped dimer

    Structural, biochemical and in vivo analyses reveal that Rad50 zinc-hook and coiled-coil domains form a novel dimerization interface essential for Mre11-complex function in DNA damage response and repair.

    Young Bong Park, Marcel Hohl, Michał Padjasek… in Nature Structural & Molecular Biology (2017)

  3. No Access

    Article

    Crystal structure of human DGCR8 core

    A complex of Drosha with DGCR8 (or its homolog Pasha) cleaves primary microRNA (pri-miRNA) substrates into precursor miRNA and initiates the microRNA maturation process. Drosha provides the catalytic site for ...

    Sun Young Sohn, Won ** Bae, Jeong Joo Kim… in Nature Structural & Molecular Biology (2007)

  4. No Access

    Article

    Structure-based identification of a novel NTPase from Methanococcus jannaschii

    Almost half of the entire set of predicted genomic products from Methanococcus jannaschii are classified as functionally unknown hypothetical proteins. We present a structure-based identification of the biochemic...

    Kwang Yeon Hwang, Ji Hyung Chung, Sung-Hou Kim, Ye Sun Han… in Nature Structural Biology (1999)

  5. No Access

    Article

    Structure and mechanism of glutamate racemase from Aquifex pyrophilus

    Glutamate racemase (MurI) is responsible for the synthesis of D-glutamate, an essential building block of the peptidoglycan layer in bacterial cell walls. The crystal structure of glutamate racemase from Aquifex ...

    Kwang Yeon Hwang, Chun-Seok Cho, Sang Suk Kim, Ha-Chin Sung… in Nature Structural Biology (1999)

  6. No Access

    Article

    The crystal structure of flap endonuclease-1 from Methanococcus jannaschii

    Flap endonuclease-1 (FEN-1), a structure specific nuclease, is an essential enzyme for eukaryotic DNA replication and repair. The crystal structure of FEN-1 from Methanococcus jannaschii, determined at 2.0 Å reso...

    Kwang Yeon Hwang, Kyuwon Baek, Hye-Yeon Kim, Yunje Cho in Nature Structural Biology (1998)

  7. No Access

    Article

    Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box

    The pocket region of retinoblastoma tumour suppressor (Rb) is essential for tumour suppressing activity. The Rb pocket is primarily composed of two domains, A and B. We have determined the X-ray crystal struct...

    Hye-Yeon Kim, Yunje Cho in Nature Structural Biology (1997)