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Article
The Aging Biomarker Consortium represents a new era for aging research in China
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Article
Biomarkers of aging
Aging biomarkers are a combination of biological parameters to (i) assess age-related changes, (ii) track the physiological aging process, and (iii) predict the transition into a pathological status. Although ...
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Article
Hydrothermal carbon modified Cu–Fe oxide with enhanced Fe(II)/Fe(III) cycle to activate peroxydisulfate for phenol removal
Phenol is a typical organic pollutant in wastewater, which will cause considerable damage and threat to the ecosystem and human health. In this work, hydrothermal carbon (HTC) modified copper-iron oxide (CFO) ...
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Article
Open AccessHigh-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity
Duloxetine (DLX) has been approved for the successful treatment of psychiatric diseases, including major depressive disorder, diabetic neuropathy, fibromyalgia and generalized anxiety disorder. However, since ...
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Article
Performance study of amorphous NiB alloys modified by Mo as electrocatalysts for borohydride oxidation
In this study, amorphous Ni–B–Mox/C alloy catalysts are prepared by a convenient way of chemical reduction. The activity of the Ni–B–Mo/C catalysts with various ratios of Mo to B toward electro-oxidation of boroh...
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Article
Evaluation of Co–Au bimetallic nanoparticles as anode electrocatalyst for direct borohydride-hydrogen peroxide fuel cell
Carbon-supported Co–Au bimetallic nanoparticles with different Co/Au atomic ratios were prepared through two-step reduction in a reverse microemulsion system. The prepared catalysts were investigated as anode ...
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Article
Open AccessHuman primary epidermal organoids enable modeling of dermatophyte infections
Technology of generating human epidermal derivatives with physiological relevance to in vivo epidermis is continuously investigated for improving their effects on modeling of human natural dermatological statu...
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Repair and Regeneration After Important Visceral Injury
Visceral organs are the participants and maintainers of various life activities of the body. Various injuries such as trauma, surgery, organ transplantation, inflammatory bowel disease, and other serious disea...
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Article
Open AccessEnhanced differentiation of human pluripotent stem cells into pancreatic endocrine cells in 3D culture by inhibition of focal adhesion kinase
Generation of insulin-producing cells from human pluripotent stem cells (hPSCs) in vitro would be useful for drug discovery and cell therapy in diabetes. Three-dimensional (3D) culture is important for the acq...
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Article
Open AccessAuthor Correction: Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury
We report the generation of human ESC-derived, expandable hepatic organoids (hEHOs) using our newly established method with wholly defined (serum-free, feeder free) media. The hEHOs stably maintain phenotypic ...
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Article
Open AccessSweat gland organoids contribute to cutaneous wound healing and sweat gland regeneration
Sweat glands perform a vital thermoregulatory function in mammals. Like other skin components, they originate from epidermal progenitors. However, they have low regenerative potential in response to injury. We...
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Article
Enhancement in photocatalytic performance of Ag–AgCl decorated with h-WO3 and mechanism insight
A h-WO3 decorated Ag–AgCl composite was prepared through facile precipitation and photoreduction methods and demonstrated to be a highly efficient and stable photocatalyst for the degradation of Rhodamine B (RhB)...
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Article
Optimized design of novel Pt decorated 3D BiOBr flower-microsphere synthesis for highly efficient photocatalytic properties
3D BiOBr flower-microspheres decorated with small amount (0.02–0.5 wt%) of Pt nanoparticles were successfully prepared via new electrostatic-adsorption-assisted light-reduction route. The as-prepared samples w...
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Article
Performance evaluation of borohydride electrooxidation reaction with ternary alloy Au–Ni–Cu/C catalysts
Carbon-supported Au–Ni–Cu, Au–Ni, Au–Cu and Au nanoparticles were synthesised using a polyol reduction method. The prepared nanoparticle catalysts were used as anode electrocatalysts in direct borohydride–hydr...
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Article
Open AccessConnexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes
Bi-potential hepatic progenitor cells can give rise to both hepatocytes and cholangiocytes, which is the last phase and critical juncture in terms of sequentially hepatic lineage restriction from any kind of s...
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Article
Open AccessConnexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells
Gap junction-mediated cell-cell interactions are highly conserved and play essential roles in cell survival, proliferation, differentiation and patterning. We report that Connexin 32 (Cx32)-mediated gap juncti...
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Article
Investigation of carbon-supported Ni@Ag core-shell nanoparticles as electrocatalyst for electrooxidation of sodium borohydride
Carbon-supported Ni@Ag core-shell nanoparticles were synthesized and used as the anode electrocatalyst for direct borohydride-hydrogen peroxide fuel cell (DBHFC). The morphology, structure, and composition of ...
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Article
Citric acid-assisted synthesis of nano-Ag/BiOBr with enhanced photocatalytic activity
In this study, silver nano-particles have been anchored in the surface of BiOBr photocatalysts by a citric acid-assisted photoreduction method. The citric acid was served as a chelating and reductive agent for...
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Article
Involvement of RhoA/ROCK in insulin secretion of pancreatic β-cells in 3D culture
Cell-cell contacts and interactions between pancreatic β-cells and/or other cell populations within islets are essential for cell survival, insulin secretion, and functional synchronization. Three-dimensional ...
