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Article
The complete chloroplast genome sequence and phylogenetic relationship analysis of Eomecon chionantha, one species unique to China
Eomecon chionantha Hance, an endemic species in China, has a long medical history in Chinese ethnic minority medicine and is known for its anti-inflammatory and analgesic effects. However, studies of E. chionanth...
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Article
Open AccessExploring the dynamic adaptive responses of Epimedium pubescens to phosphorus deficiency by Integrated transcriptome and miRNA analysis
Phosphorus, a crucial macronutrient essential for plant growth and development. Due to widespread phosphorus deficiency in soils, phosphorus deficiency stress has become one of the major abiotic stresses that ...
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Article
Cardiac Metabolism, Reprogramming, and Diseases
Cardiovascular diseases (CVD) account for the largest bulk of deaths worldwide, posing a massive burden on societies and the global healthcare system. Besides, the incidence and prevalence of these diseases ar...
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Article
Comparative complete chloroplast genome of Geum japonicum: evolution and phylogenetic analysis
Geum japonicum (Rosaceae) has been widely used in China as a traditional herbal medicine due to its high economic and medicinal value. However, the appearance of Geum species is relatively similar, making identif...
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Article
Physical dynamic double-network hydrogels as dressings to facilitate tissue repair
Double-network hydrogels can be tuned to have high mechanical strength, stability, elasticity and bioresponsive properties, which can be combined to create self-healing, adhesive and antibacterial wound dressi...
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Article
Piezocatalytic removal of water bacteria and organic compounds: a review
In the context of climate change, freshwater shrinkage and industrialization, human diseases are increasing due to water pollution by toxic chemicals and pathogenic bacteria, calling for advanced methods to tr...
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Article
Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism
Monoterpenoid indole alkaloids (MIAs) are among the most diverse specialized metabolites in plants and are of great pharmaceutical importance. We leveraged single-cell transcriptomics to explore the spatial or...
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Article
Antibacterial conductive self-healable supramolecular hydrogel dressing for infected motional wound healing
Wounds on stretchable parts of the human body cause prolonged suffering and involve more severe healing processes than wounds on stationary parts. However, they have received insufficient attention compared wi...
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Article
Structural and Functional Design of Electrospun Nanofibers for Hemostasis and Wound Healing
Electrospun nanofibers have been extensively studied in the biomedical field, including the controlled release of drugs, bionics, cell scaffolds, hemostasis, wound healing, and tissue engineering because of th...
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Article
Open AccessBioinspired Injectable Self-Healing Hydrogel Sealant with Fault-Tolerant and Repeated Thermo-Responsive Adhesion for Sutureless Post-Wound-Closure and Wound Healing
Mussel and brown algae inspired dual-bionic bioadhesive cross-linked by dynamic bonds exhibits good self-healing capacity and sufficient adhesive strength....
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Article
Open AccessIRES-mediated Wnt2 translation in apoptotic neurons triggers astrocyte dedifferentiation
Reactive astrogliosis usually bears some properties of neural progenitors. How injury triggers astrocyte dedifferentiation remains largely unclear. Here, we report that ischemia induces rapid up-regulation of ...
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Article
Publisher Correction: Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans
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Article
Open AccessConductive Biomaterials as Bioactive Wound Dressing for Wound Healing and Skin Tissue Engineering
The design and application of conductive biomaterials for wound healing are comprehensively reviewed, including versatile conductive agents, the various fo...
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Article
Haemostatic materials for wound healing applications
Wounds are one of the most common health issues, and the cost of wound care and healing has continued to increase over the past decade. The first step in wound healing is haemostasis, and the development of ha...
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Article
Open AccessInjectable Self-Healing Adhesive pH-Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing
A series of novel injectable pH-responsive self-healing hydrogels with enhanced adhesive strength were prepared.
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Article
Open AccessHuman primary epidermal organoids enable modeling of dermatophyte infections
Technology of generating human epidermal derivatives with physiological relevance to in vivo epidermis is continuously investigated for improving their effects on modeling of human natural dermatological statu...
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Article
Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans
Recent success in identifying gene-regulatory elements in the context of recombinant adeno-associated virus vectors has enabled cell-type-restricted gene expression. However, within the cerebral cortex these t...
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Article
Open AccessVisible-light-assisted multimechanism design for one-step engineering tough hydrogels in seconds
Tough hydrogels that are capable of efficient mechanical energy dissipation and withstanding large strains have potential applications in diverse areas. However, most reported fabrication strategies are perfor...
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Article
Open AccessSingle-Cell Analysis for Glycogen Localization and Metabolism in Cultured Astrocytes
Cerebral glycogen is principally localized in astrocytes rather than in neurons. Glycogen metabolism has been implicated in higher brain functions, including learning and memory, yet the distribution patterns ...
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Article
Distinct subnetworks of the thalamic reticular nucleus
The thalamic reticular nucleus (TRN), the major source of thalamic inhibition, regulates thalamocortical interactions that are critical for sensory processing, attention and cognition1–5. TRN dysfunction has been...
