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Article
Open AccessTherapeutic potential of berberine in attenuating cholestatic liver injury: insights from a PSC mouse model
Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by progressive biliary inflammation and bile duct injury. Berberine (BBR) is a bioactive isoquinoline alkaloid found in various her...
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Article
Open AccessReduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice
Alcohol use disorder is a major cause of morbidity, which requires newer treatment approaches. We previously showed in a randomized clinical trial that alcohol craving and consumption reduces after fecal trans...
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Article
Open AccessRNA binding protein HuR protects against NAFLD by suppressing long noncoding RNA H19 expression
NAFLD has become the most common chronic liver disease worldwide. Human antigen R (HuR), an RNA-binding protein, is an important post-transcriptional regulator. HuR has been reported as a key player in regulat...