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Open AccessPredictive values of early head computed tomography for survival outcome after cardiac arrest in childhood: a pilot study
Predicting outcomes of children after cardiac arrest (CA) remains challenging. To identify useful prognostic markers for pediatric CA, we retrospectively analyzed the early findings of head computed tomography...
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Environmental Quality Analysis
Environmental quality assessments require the determination of concentrations of various substances. This chapter outlines key points for environmental quality analysis. First, environmental standard values (e...
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Article
Open AccessThe origin of β-strand bending in globular proteins
Many β-strands are not flat but bend and/or twist. However, although almost all β-strands have a twist, not all have a bend, suggesting that the underlying force(s) driving β-strand bending is distinct from th...
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Article
α-N-Acetylglucosaminidase from Bifidobacterium bifidum specifically hydrolyzes α-linked N-acetylglucosamine at nonreducing terminus of O-glycan on gastric mucin
α-Linked N-acetylglucosamine is one of the major glyco-epitopes in O-glycan of gastroduodenal mucin. Here, we identified glycoside hydrolase (GH) family 89 α-N-acetylglucosaminidase, termed AgnB, from Bifidobacte...
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Open AccessProbable rapid eye movement sleep behavior disorder, nocturnal disturbances and quality of life in patients with Parkinson’s disease: a case-controlled study using the rapid eye movement sleep behavior disorder screening questionnaire
Increasing evidence provides a clear association between rapid eye movement sleep behavior disorders (RBD) and Parkinson’s disease (PD), but the clinical features that determine the co-morbidity of RBD and PD ...
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Evaluation of contributing factors to restless legs syndrome in migraine patients
Recent studies have provided evidence for a positive association between migraine and restless legs syndrome (RLS), although the exact mechanisms and contributing factors remain unclear. A cross-sectional, cas...
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Open AccessComputational prediction and experimental validation of evolutionarily conserved microRNA target genes in bilaterian animals
In many eukaryotes, microRNAs (miRNAs) bind to complementary sites in the 3'-untranslated regions (3'-UTRs) of target messenger RNAs (mRNAs) and regulate their expression at the stage of translation. Recent st...
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Improvement of a Candida antarctica lipase B-displaying yeast whole-cell biocatalyst and its application to the polyester synthesis reaction
A Candida antarctica lipase B (CALB)-displaying yeast whole-cell biocatalyst was constructed with the integration of the CALB cell-surface display expression cassette in the yeast genome and cell fusion by mating...
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Article
Long-term Follow-up of Busulfan, Etoposide, and Nimustine Hydrochloride (ACNU) or Melphalan as Conditioning Regimens for Childhood Acute Leukemia and Lymphoma
We retrospectively evaluated early and long-term complications of an intensified conditioning regimen consisting of busulfan and etoposide in combination with either nimustine hydrochloride (ACNU) (BVA regimen...
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Efficacy of the Levodopa on Frontal Lobe Dysfunction in Patients with de Novo Parkinson’s Disease; A Study Using the Event-related Potential
We investigated the efficacy of the levodopa on cognitive function in patients with de novo Parkinson’s disease (PD) using the event related potential (ERP) measure and neuropsychological test batteries. We st...
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Detection of the Membrane Protein Recognized by the Kidney-Specific Alkylglucoside Vector
Purpose. Previously, we suggested that alkylglucoside can be aneffective vector for renal-specific drug delivery (Suzuki et al., J. Pharmacol.Exp. Ther., 288:57–61, 1999). The purpose of the present study is toc...
