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Yong-**u **ng
Psychiatry
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Article
Nefiracetam (DM-9384): effect on eyeblink classical conditioning in older rabbits
The nootropic compound nefiracetam was evaluated in 88 older rabbits in a 750-ms delay paradigm of eyeblink classical conditioning (EBCC). Rabbits (mean age=28.7 months) were assigned in groups of eight to one...
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Article
Effects of the AMPA receptor antagonist NBQX on the development and expression of behavioral sensitization to cocaine and amphetamine
We examined the effect of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX), an antagonist of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of glutamate receptor, on the deve...
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Article
Can the ”state-dependency” hypothesis explain prevention of amphetamine sensitization in rats by NMDA receptor antagonists?
Many laboratories have reported that coadministration of N-methyl-d-aspartate (NMDA) receptor antagonists with psychomotor stimulants prevents the development of behavioral sensitization and therefore concluded ...
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Article
Effect of the κ opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice
While the effects of several kappa opioid receptor agonists on cocaine-induced reward have been studied, such effects of R-84760, a novel non-peptidic, potent and selective kappa opioid agonist that has been s...
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Article
Hippocampal shape deformity analysis in obsessive–compulsive disorder
Abnormalities of orbital prefrontal cortex and caudate nuclei have, thus far, been the main findings regarding the pathophysiology of obsessive–compulsive disorder (OCD). On the other hand, neuroimaging studie...
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Article
Effects of early postnatal sibling deprivation on anxiety and vulnerability to cocaine in offspring rats
Early-life experience has long-term consequences on affective behavior and drug abuse in adults. While many manipulations used to study these consequences alter mother–infant interactions, the effects of sibli...
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Article
In vitro study of haematoporphyrin monomethyl ether-mediated sonodynamic effects on C6 glioma cells
To study the cytotoxicity induced by haematoporphyrin monomethyl ether (HMME)-mediated sonodynamic therapy (SDT) on C6 glioma cells.
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Article
Depressive symptoms in elementary school children in Jeju Island, Korea: prevalence and correlates
We investigated the prevalence and correlates of depressive symptoms in elementary school children in Jeju Island, Korea. The study participants were 2305 children enrolled in elementary schools in Jeju-si, Se...
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Article
No evidence of perfusion abnormalities in the basal ganglia of a patient with generalized chorea-ballism and polycythaemia vera: analysis using subtraction SPECT co-registered to MRI
Polycythaemia vera is a well-known cause of symptomatic chorea, however, the pathophysiology of this correlation remains unclear. We report on a patient with generalized chorea-ballism associated with polycyth...
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Article
Multimodal Magnetic Resonance Imaging for Brain Disorders: Advances and Perspectives
Modern brain imaging technologies play essential roles in our understanding of brain information processing and the mechanisms of brain disorders. Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging ...
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Book
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Chapter
Future Directions for Behavior Genetics
The Handbook has been organized into (1) an introduction; (2) quantitative methods and models in behavior genetics; (3) genetics of cognition; (4) genetics of personality; (5) genetics of psychopathology; and ...
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Chapter
Sexual Selection and Aggressive Behavior in Drosophila
In animals, females make large but few nutritious eggs and males produce small but many mobile sperm. There are tremendous amounts of competition between males over access to females, and females discriminate ...
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Article
Functional Interactions between Endocannabinoid and CCK Neurotransmitter Systems May Be Critical for Extinction Learning
The endocannabinoid system and the cannabinoid type 1 receptor (CB1R) are required for the extinction of conditioned fear. CB1 antagonists have been shown to prevent extinction when delivered both systemically...
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Article
Behavioral and Neurochemical Changes Induced by Oxycodone Differ Between Adolescent and Adult Mice
Nonmedical use of the prescription opioid analgesic oxycodone is a major problem in the United States, particularly among adolescents and young adults. This study characterized self-administration of oxycodone...
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Article
Differential Effects of the CRF-R1 Antagonist GSK876008 on Fear-Potentiated, Light- and CRF-Enhanced Startle Suggest Preferential Involvement in Sustained vs Phasic Threat Responses
The amplitude of the acoustic startle response is increased when elicited in the presence of brief cues that predict shock (fear-potentiated startle) and also when elicited during sustained exposure to bright ...
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Article
Mental Symptoms in Different Health Professionals During the SARS Attack: A Follow-up Study
Aim The aims of the study were to assess the psychological impact of SARS bio-disaster on healthcare workers. Methods The participants were 127 healthcare workers who had taken care of su...
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Article
Abstracts for the 6th Congress of Asian Sleep Research Society
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Article
Bovine serum albumin promotes IL-1β and TNF-α secretion by N9 microglial cells
Bovine serum albumin (BSA) is generally used in biomedical experiments. In the solution of some reagents, BSA is necessary to maintain the stability and concentration of the effective component. Therefore, the...
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Article
Peripheral cholinoceptor antagonist anisodamine counteracts cholinergic adverse effects and facilitates cognitive amelioration of rivastigmine
Rivastigmine is a potent acetyl- and butyrylcholinesterase inhibitor widely used for cognitive improvement in Alzheimer’s disease (AD) therapy. However, dose-limiting adverse effects restrict its tolerability ...
