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Article
Effects of early postnatal sibling deprivation on anxiety and vulnerability to cocaine in offspring rats
Early-life experience has long-term consequences on affective behavior and drug abuse in adults. While many manipulations used to study these consequences alter mother–infant interactions, the effects of sibli...
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Article
Conditioned drug reward enhances subsequent spatial learning and memory in rats
Chronic exposure to drugs of abuse alters neural processes that normally promote learning and memory. A context that is repeatedly paired with reinforcing drugs will acquire secondary reinforcing properties (c...
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Article
Clonidine attenuates morphine withdrawal and subsequent drug sensitization in rhesus monkeys
Clonidine is an α2 adrenoceptor agonist that is frequently used to reduce withdrawal symptoms during opioid detoxification in humans. The long-term effects of clonidine on withdrawal symptoms and its effects on s...