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    Article

    Effects of early postnatal sibling deprivation on anxiety and vulnerability to cocaine in offspring rats

    Early-life experience has long-term consequences on affective behavior and drug abuse in adults. While many manipulations used to study these consequences alter mother–infant interactions, the effects of sibli...

    Yan-Qin Li, **ao-Yi Wang, Hai-feng Zhai, Yong-Qiu Zheng in Psychopharmacology (2008)

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    Article

    Conditioned drug reward enhances subsequent spatial learning and memory in rats

    Chronic exposure to drugs of abuse alters neural processes that normally promote learning and memory. A context that is repeatedly paired with reinforcing drugs will acquire secondary reinforcing properties (c...

    Hai-feng Zhai, Zhang-Yin Zhang, Mei Zhao, Yi Qiu, Udi E. Ghitza in Psychopharmacology (2007)

  3. Article

    Clonidine attenuates morphine withdrawal and subsequent drug sensitization in rhesus monkeys

    Clonidine is an α2 adrenoceptor agonist that is frequently used to reduce withdrawal symptoms during opioid detoxification in humans. The long-term effects of clonidine on withdrawal symptoms and its effects on s...

    Su-qing Chen, Hai-feng Zhai, Yan-ying Cui, Jie Shi in Acta Pharmacologica Sinica (2007)