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Article
Performance of ChatGPT on the Taiwan urology board examination: insights into current strengths and shortcomings
To compare ChatGPT-4 and ChatGPT-3.5's performance on Taiwan urology board examination (TUBE), focusing on answer accuracy, explanation consistency, and uncertainty management tactics to minimize score penalti...
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Article
Open AccessFinite element analysis after rod fracture of the spinal hybrid elastic rod system
The spinal hybrid elastic (SHE) rod dynamic stabilization system can provide sufficient spine support and less adjacent segment stress. This study aimed to investigate the biomechanical effects after the inter...
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Article
Materials Properties and Application Strategy for Ligament Tissue Engineering
Accompanied by clinical and health requirements, ligament tissue engineering has been constantly promoted. Autografts and allografts, due to their limitations and economic benefits, are gradually replaced by a...
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Article
Comparison of Osseointegration in Different Intravertebral Fixators
Percutaneous minimally invasive spinal surgery is performed to manage vertebral compression fractures. The novel modular spine block (MSB) is a spinal fixator designed to provide cementless intravertebral fixa...
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Article
Transdermal drug delivery systems for fighting common viral infectious diseases
Transdermal drug delivery systems (TDDS) have many advantages and represent an excellent alternative to oral delivery and hypodermic injections. TDDS are more convenient and less invasive tools for disease and...
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Article
The use of micro-needle arrays to deliver cells for cellular therapies
Cell therapy is used to treat various diseases and to repair injuries. Cell delivery is a crucial process that delivers cells to target sites. Cells must be precisely delivered to a target site and the cells t...
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Article
Role of Sodium Taurocholate Cotransporting Polypeptide as a New Reporter and Drug-Screening Platform: Implications for Preventing Hepatitis B Virus Infections
Sodium taurocholate cotransporting polypeptide (NTCP) is a transmembrane protein responsible for delivering indocyanine green (ICG), an ideal infrared fluorescent dye, from extracellular space into the cytopla...
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Article
Open AccessLeading Comorbidity associated with 30-day post-anesthetic mortality in geriatric surgical patients in Taiwan: a retrospective study from the health insurance data
Elderly patients with aged physical status and increased underlying disease suffered from more postoperative complication and mortality. We design this retrospective cohort study to investigate the relationshi...
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Article
Open AccessOptimized decellularization protocol including α-Gal epitope reduction for fabrication of an acellular porcine annulus fibrosus scaffold
Recent advances in tissue engineering have led to potential new strategies, especially decellularization protocols from natural tissues, for the repair, replacement, and regeneration of intervertebral discs. ...
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Article
Open AccessTreatment of critically sized femoral defects with recombinant BMP-2 delivered by a modified mPEG-PLGA biodegradable thermosensitive hydrogel
Reconstruction of a segmental fracture with massive bone loss is still a challenge for orthopaedic surgeons. The aim of our study was to develop a suitable biodegradable thermosensitive hydrogel system as a ca...
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Article
Open AccessFabrication and properties of acellular porcine anulus fibrosus for tissue engineering in spine surgery
Over the last few years, new treatments for a damaged intervertebral disc (IVD) have included strategies to repair, replace, or regenerate the degenerative disc. However, these techniques are likely to have li...
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Chapter and Conference Paper
A Web-Based Information System Applied on Utilization/Benefit Management of Medical Equipment in Hospital
Intelligent management of medical equipments is vital to hospital. Most hospitals spend large budgets in purchasing medical equipments, but there is no perfect monitoring mechanism to immediately understand th...
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Article
Evaluation of transdifferentiation from mesenchymal stem cells to neuron-like cells using microfluidic patterned co-culture system
We design a microfluidic patterned co-culture system for mouse mesenchymal stem cells (mMSCs) and neural cells to demonstrate the paracrine effects produced by the neural cells in facilitating the transdiffere...
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Article
Patterned PDMS based cell array system: a novel method for fast cell array fabrication
Cell-cell interaction is important in numerous biological processes, including cell growth, cell differentiation and migration. The ability to generate pre-determined cell patterns or cell arrays on a study su...
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Chapter and Conference Paper
Enzymatic amplification combined with nanoparticles-based detection for Microarray
The development of techniques for parallel analysis of biomolecules such as proteins or oligonucleotides is still continuing [1]. Many researchers have always focused their work on achieving an improvement reg...
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Article
Response Surface Method: A Novel Strategy to Optimize lontophoretic Transdermal Delivery of Thyrotropin-releasing Hormone
Purpose. To maximize the iontophoretic transdermal delivery rate of thyrotropin-releasing hormone (TRH) facilitated by periodically monophase-pulsed current across excised skin.
