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Article
Open AccessSciatica caused by spinal epidural abscess as the initial clinical presentation of colon cancer: a rare case report and review of literature
Colorectal cancer is one of the most frequently diagnosed forms of cancer, and it is associated with several common symptoms and signs such as rectal bleeding, altered bowel habits, abdominal pain, anemia, and...
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Article
Open AccessPullout strength of different pedicle screws after primary and revision insertion: an in vitro study on polyurethane foam
Surgeons are routinely required to remove loose or failed pedicle screws and insert a new screw in their place. However, inserting a new screw into an existing hole may compromise the holding capacity of the p...
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Article
Open AccessEffects of applying platelet-rich plasma during arthroscopic rotator cuff repair: a systematic review and meta-analysis of randomised controlled trials
Because of its healing properties, platelet-rich plasma (PRP) has been applied to the bone–tendon interface during arthroscopic rotator cuff repair to improve surgical outcomes. However, its effects remain amb...
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Article
Open AccessOptimized decellularization protocol including α-Gal epitope reduction for fabrication of an acellular porcine annulus fibrosus scaffold
Recent advances in tissue engineering have led to potential new strategies, especially decellularization protocols from natural tissues, for the repair, replacement, and regeneration of intervertebral discs. ...
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Article
Open AccessThe effect of annular repair on the failure strength of the porcine lumbar disc after needle puncture and punch injury
The purpose was to quantify the structural integrity of annulus fibrosis (AF) after injuries with repair.
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Article
In vitro Penetration and in vivo Distribution of Honokiol into the Intervertebral Disc in Rat
Honokiol is a potential candidate for the treatment of intervertebral disc (IVD) degeneration. In this study, we develop in vitro and in vivo methods to detect the distribution of honokiol in intervertebral discs...
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Article
Open AccessFabrication and properties of acellular porcine anulus fibrosus for tissue engineering in spine surgery
Over the last few years, new treatments for a damaged intervertebral disc (IVD) have included strategies to repair, replace, or regenerate the degenerative disc. However, these techniques are likely to have li...
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Article
Mechanical stress-induced apoptosis of nucleus pulposus cells: an in vitro and in vivo rat model
Un-physiological loads play an important role in the degenerative process of inter-vertebral discs (IVD). In this study, we used an in vitro and in vivo rat model to investigate the mechanism of nucleus pulpos...
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Article
Open AccessIsoflavones prevent bone loss following ovariectomy in young adult rats
Soy protein, a rich source of phytoestrogens, exhibit estrogen-type bioactivity. The purpose of this study was to determine if ingestion of isoflavones before ovariectomy can prevent bone loss following ovarie...
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Article
Open AccessIsokinetic eccentric exercise can induce skeletal muscle injury within the physiologic excursion of muscle-tendon unit: a rabbit model
Intensive eccentric exercise can cause muscle damage. We simulated an animal model of isokinetic eccentric exercise by repetitively stretching stimulated triceps surae muscle-tendon units to determine if such ...
