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    Article

    A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation

    Viral and host factors influence the rate of HIV-1 disease progression1. For HIV-1 to fuse, a CD4+ cell must express a co-receptor that the virus can use2,3. The chemokine receptors CCR5 and CXCR4 are used by ...

    Leondios G. Kostrikis, Yaoxing Huang, John P. Moore, Steve M. Wolinsky… in Nature Medicine (1998)

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    Article

    The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

    A 32–nucleotide deletion (δ32) within the β–chemokine receptor 5 (CCR5) gene has been described in subjects who remain uninfected despite extensive exposure to HIV–1. This allele was found to be common in the ...

    Yaoxing Huang, William A. Paxton, Steven M. Wolinsky, Avidan U. Neumann… in Nature Medicine (1996)