14 Result(s)

Article

HCV Phylogeography of the General Population and High-Risk Groups in Cyprus Identifies the Island as a Global Sink for and Source of Infection

Hepatitis C virus (HCV) genotype and subtype distribution differs according to geographic origin and transmission risk category. Previous molecular epidemiology studies suggest the presence of multiple subtype...

Dimitrios Paraskevis, Dora C. Stylianou, Johana Hezka… in Scientific Reports (2019)

Article

HIV-1 Infection in Cyprus, the Eastern Mediterranean European Frontier: A Densely Sampled Transmission Dynamics Analysis from 1986 to 2012

Since HIV-1 treatment is increasingly considered an effective preventionstrategy, it is important to study local HIV-1 epidemics to formulate tailored preventionpolicies. The prevalence of HIV-1 in Cyprus was ...

Andrea-Clemencia Pineda-Peña, Kristof Theys, Dora C. Stylianou… in Scientific Reports (2018)

Article

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data fr...

Dineke Frentz, David AMC Van de Vijver, Ana B Abecasis… in BMC Infectious Diseases (2014)

Article

Limited cross-border infections in patients newly diagnosed with HIV in Europe

International travel plays a role in the spread of HIV-1 across Europe. It is, however, not known whether international travel is more important for spread of the epidemic as compared to endogenous infections ...

Dineke Frentz, Annemarie M J Wensing, Jan Albert, Dimitrios Paraskevis… in Retrovirology (2013)

Article

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment,...

Kristof Theys, Koen Deforche, Jurgen Vercauteren, Pieter Libin… in Retrovirology (2012)

Article

Influx of uncommon HIV-1 strains from Eastern Europe and identification of a new unique recombinant strain among young Cypriot MSM in Cyprus

Ioanna Kousiappa, Yiota Lazarou, Katerina M Othonos, Johana Hezka… in Retrovirology (2012)

Article

Molecular epidemiology and drug resistance prevalence of strains from newly diagnosed HIV-1 patients in Northern Greece during 2009-2010

Zoe Antoniadou, Ioanna Kousiappa, Johana Hezka, Lemonia Skoura… in Retrovirology (2012)

Article

Molecular epidemiology of hepatitis C infection in Cyprus within the general population and high-risk cohorts

Initial data on the molecular epidemiology of HCV infection in Cyprus showed a highly polyphyletic infection and multiple points of introduction into the general population. The continuation and expansion of t...

Victoria L Demetriou, Leondios G Kostrikis in BMC Research Notes (2011)

Article

Development of a molecular-beacon-based multi-allelic real-time RT-PCR assay for the detection of human coronavirus causing severe acute respiratory syndrome (SARS-CoV): a general methodology for detecting rapidly mutating viruses

Emerging infectious diseases have caused a global effort for development of fast and accurate detection techniques. The rapidly mutating nature of viruses presents a major difficulty, highlighting the need for...

Andreas V. Had**icolaou, Gabriella A. Farcas… in Archives of Virology (2011)

Article

Implications of hcv natural genetic diversity on HCV NS5B inhibitor NM283

Victoria L Demetriou, Leondios G Kostrikis in Retrovirology (2010)

Article

Molecular beacon-based real-time PCR detection of primary isolates of Salmonella Typhimurium and Salmonella Enteritidis in environmental and clinical samples

A fast and simple two-step multiplex real-time PCR assay has been developed to replace the traditional, laborious Salmonella seroty** procedure. Molecular beacons were incorporated into the assay as probes f...

Andreas V Had**icolaou, Victoria L Demetriou, Maria A Emmanuel… in BMC Microbiology (2009)