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Article
Open AccessComparison of anal function and quality of life after conformal sphincter preservation operation and intersphincteric resection of very low rectal cancer: a multicenter, retrospective, case–control analysis
Conformal sphincter preservation operation (CSPO) is a sphincter preservation operation for very low rectal cancers. Compared to intersphincteric resection (ISR), CSPO retains more dentate line and distal rect...
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Article
Numerical Simulation and Experimental Study of the Compressive Energy Absorption Characteristics of a Multi-Layered Gradient Egg-Box Structure
Gradient structures provide graded stiffness and multiple energy-absorbing steps for better energy absorption. In practical applications, multilayer gradient egg-box structures can be efficiently and inexpensi...
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Article
A Numerical Investigation on the Drying Process of Laminated Green Body Manufactured by 3D Gel-Printing of Metal Power
In order to predict the temperature, humidity and deformation of the 3D gel-printing metal laminated green body during the drying process. This paper presents a mathematical model of solving the coupled temper...
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Article
Influence of olfactory dysfunction on the perception of food
Eating-related problems are among the most frequent issues in olfactory impairment, causing a noticeable loss of quality of life for some of the affected persons. To what extent olfactory dysfunction impacts o...
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Article
Thermomechanical Coupling Model for a Stainless Steel-Clad Plate on Heat Treatment
Quick and correct prediction of the internal stress and deformation of stainless steel-clad plates on heat treatment is a problem of specific interest. A thermomechanical coupling model based on the engineerin...
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Article
Prediction of a High Temperature Bonding Condition at the Interface for the Hot-Rolled Stainless Steel Clad Plate on Rolling
The stainless steel-carbon steel clad plate was investigated using the theoretical analysis of various factors influencing the high-temperature interfacial bonding during its rolling. Phenomenological predicti...
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Article
Open AccessEAF2 regulates DNA repair through Ku70/Ku80 in the prostate
Androgens are known to protect prostate cancer cells from DNA damage. Recent studies showed regulation of DNA repair genes by androgen receptor signaling in prostate cancers. ELL-associated factor 2 (EAF2) is ...
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Article
Failure Analysis of a Sheet Metal Blanking Process Based on Damage Coupling Model
In this paper, a blanking process of sheet metal is studied by the methods of numerical simulation and experimental observation. The effects of varying technological parameters related to the quality of produc...
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Article
Studies on protective effects of human paraoxonases 1 and 3 on atherosclerosis in apolipoprotein E knockout mice
Paraoxonase (PON) possesses antiatherogenic potentials, but the distinct functions of PON members in alleviating atherosclerosis are not yet clear. This study aimed to evaluate the protective effects of hPON1 ...
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Article
Dasatinib promotes ATRA-induced differentiation of AML cells
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Article
Correlation of Mammographic Calcifications with HER-2/neu Overexpression in Primary Breast Carcinomas
HER-2/neu is a valuable therapeutic and prognostic marker in primary breast carcinomas. The aim of this study was to evaluate the association between mammographic calcifications and HER-2/neu overexpression in...
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Article
Skewed T-cell receptor BV14 and BV16 expression, and shared complementarity-determining region 3 sequence and common sequence motifs in synovial T cells of rheumatoid arthritis
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Article
T cell activation with systemic agonistic antibody versus local 4-1BB ligand gene delivery combined with interleukin-12 eradicate liver metastases of breast cancer
We have shown that interleukin-12 (IL-12) generated a strong, albeit transient, anti-tumor response, mostly mediated by natural killer (NK) cell. T cell participation, in addition to NK cells, was essential fo...
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Article
Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells
The novel synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid (AHPN/CD437) has been proven to be a potent inducer of apoptosis in a variety of tumor cell types. However, the mec...
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Article
EPR properties of mixed-valent μ-oxo and μ-hydroxo dinuclear iron complexes produced by radiolytic reduction at 77 K
Radiolytic reduction at 77 K of oxo-/hydroxo-bridged dinuclear iron(III) complexes in frozen solutions forms kinetically stabilized, mixed-valent species in high yields that model the mixed-valent sites of no...
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Article
Strasbourg Hosts 950 at E-MRS Spring Meeting