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  1. Article

    Open Access

    Cognitive decrements in 1991 Gulf War veterans: associations with Gulf War illness and neurotoxicant exposures in the Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) cohorts

    During deployment, veterans of the 1991 Gulf War (GW) were exposed to multiple war-related toxicants. Roughly a third of these veterans continue to exhibit neurotoxicant induced symptoms of Gulf War Illness (G...

    D. Keating, M. Krengel, J. Dugas, R. Toomey, L. Chao, L. Steele… in Environmental Health (2023)

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  2. Article

    Open Access

    Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis

    Exposure to nerve agents, pyridostigmine bromide (PB), pesticides, and oil-well fires during the 1991 Gulf War (GW) are major contributors to the etiology of Gulf War Illness (GWI). Since the apolipoprotein E ...

    L Abdullah, A Nkiliza, D Niedospial, G Aldrich, G Bartenfelder… in Environmental Health (2023)

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  3. No Access

    Article

    Preclinical modeling of EGFR-specific antibody resistance: oncogenic and immune-associated escape mechanisms

    To define the molecular basis of secondary resistance to epidermal growth factor receptor (EGFR)-specific antibodies is crucial to increase clinical benefit in patients. The limited access to posttreatment tum...

    G Garrido, A Rabasa, C Garrido, A López, L Chao, Á M García-Lora, F Garrido… in Oncogene (2014)

  4. No Access

    Article

    Executive dysfunction in frontotemporal dementia is related to abnormalities in frontal white matter tracts

    Cognitive deficits in behavioral-variant frontotemporal dementia (bvFTD) and AD are linked to frontal and temporal lobe gray matter (GM) pathology. The aim of this study was to assess the relative contribution...

    M. C. Tartaglia, Y. Zhang, C. Racine, V. Laluz, J. Neuhaus, L. Chao… in Journal of Neurology (2012)

  5. No Access

    Article

    Correlation of Mammographic Calcifications with HER-2/neu Overexpression in Primary Breast Carcinomas

    HER-2/neu is a valuable therapeutic and prognostic marker in primary breast carcinomas. The aim of this study was to evaluate the association between mammographic calcifications and HER-2/neu overexpression in...

    X. Wang, L. Chao, L. Chen, B. Tian, G. Ma, Y. Zang, M. Hua… in Journal of Digital Imaging (2008)

  6. No Access

    Article

    Speciation Distribution of Lead and Zinc in Soil Profiles of the Shenyang Smeltery in Northeast China

    No abstract available.

    L. Chao, Q. Zhou, S. Chen, S. Cui in Bulletin of Environmental Contamination and Toxicology (2006)

  7. No Access

    Article

    Relationship between the regulatory region polymorphism of human tissue kallikrein gene and essential hypertension

    Ten alleles with length and nucleotide sequence variations were identified in the regulatory region of human tissue kallikrein gene. This present study aimed to study the polymorphisms of the regulatory region...

    H Hua, S Zhou, Y Liu, Z Wang, C Wan, H Li, C Chen, G Li… in Journal of Human Hypertension (2005)

  8. No Access

    Article

    Recombinant adeno-associated virus-mediated kallikrein gene therapy reduces hypertension and attenuates its cardiovascular injuries

    Gene therapy of hypertension requires long-term expression of a therapeutic gene to achieve stable reduction of blood pressure. Human tissue kallikrein (HK) cleaves kininogen to produce a potent vasoactive pep...

    T Wang, H Li, C Zhao, C Chen, J Li, J Chao, L Chao, X **ao, D W Wang in Gene Therapy (2004)

  9. No Access

    Article

    Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands

     The tissue kallikrein-kinin system contributes to the regulation of local blood flow, vascular permeability, inflammatory responses, and ion transport. Tissue kallikrein is a serine proteinase which produces ...

    William C. Wolf, Russell A. Harley, D. Sluce, L. Chao… in Histochemistry and Cell Biology (1998)

  10. No Access

    Article

    DNA polymorphisms in the 5′-flanking region of the human tissue kallikrein gene

    Human tissue kallikrein gene polymorphisms were identified in the promoter region by polymerase chain reaction (PCR) and DNA sequencing. One polymorphic region was identified between nucleotides –121 and –133...

    Qing Song, Julie Chao, L. Chao in Human Genetics (1997)