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Article
Correction of murine Rag1 deficiency by self-inactivating lentiviral vector-mediated gene transfer
Severe combined immunodeficiency (SCID) patients with an inactivating mutation in recombination activation gene 1 (RAG1) lack B and T cells due to the inability to rearrange immunoglobulin (Ig) and T-cell recepto...
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Article
Correction of B-cell development in Btk-deficient mice using lentiviral vectors with codon-optimized human BTK
X-linked agammaglobulinemia (XLA) is the most common primary immunodeficiency (PID) in man and caused by mutations in the Bruton’s tyrosine kinase (BTK) gene. XLA is characterized by a B-cell differentiation arre...
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Article
The Study of Rain Specific Attenuation for the Prediction of Satellite Propagation in Malaysia
Specific attenuation is the fundamental quantity in the calculation of rain attenuation for terrestrial path and slant paths representing as rain attenuation per unit distance (dB/km). Specific attenuation is ...
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Article
Flow cytometric immunobead assay for the detection of BCR–ABL fusion proteins in leukemia patients
BCR–ABL fusion proteins show increased signaling through their ABL tyrosine kinase domain, which can be blocked by specific inhibitors, thereby providing effective treatment. This makes detection of BCR–ABL aberr...
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Article
Sola dosis facit venenum. Leukemia in gene therapy trials: a question of vectors, inserts and dosage?
In clinical gene therapy trials for X-linked severe combined immunodeficiency, the development of leukemia has come up as a severe adverse effect. In all five cases, T-cell acute lymphoblastic leukemia (T-ALL)...
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Article
Association of hospital and surgeon operation volume with the incidence of postoperative endophthalmitis: Taiwan experience
To determine the association between hospital and surgeon volume with the incidence of postoperative endophthalmitis.
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Chapter
In Vitro Magnetic Resonance Scanning of Urinary Calculi
Clinical experience with ESWL has shown that the size and composition of urinary calculi affect success. Knowing the composition of a stone before treatment is therefore desirable. We have examined the role of...
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Article
Parotid haemangioma in infants: MR imaging at 1.5T
Parotid gland neoplasms are uncommon and account for less than 2% of human tumours. Haemangiomas account for about 50% of parotid tumours in infants and children compared to only 2% in adults. As the clinical ...