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    Protocol

    Repurposing Photosensitizer Proteins Through Genetic Code Expansion to Facilitate Photo-Biocatalysis

    Artificial photoenzymes with noncanonical photo-redox cofactors have paved the way for enzyme rational design and the creation of new-to-nature biocatalysts. Genetically encoded photo-redox cofactors endow pho...

    Jiangyun Wang, Yan **a, Xuzhen Guo in Genetically Incorporated Non-Canonical Amino Acids (2023)

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    Article

    Discovery of Plasma Membrane-Associated RNAs through APEX-seq

    In addition to nucleic acids, a variety of other biomolecules have also been found on the plasma membrane. Although researchers have realized that RNA has the ability to bind to membrane vesicles in vitro, lit...

    Erzhong Wu, Xuzhen Guo, Xueyi Teng, Rui** Zhang in Cell Biochemistry and Biophysics (2021)

  3. Article

    Open Access

    Significant expansion and red-shifting of fluorescent protein chromophore determined through computational design and genetic code expansion

    Fluorescent proteins (FPs) with emission wavelengths in the far-red and infrared regions of the spectrum provide powerful tools for deep-tissue and super-resolution imaging. The development of red-shifted FPs ...

    Li Wang, **an Chen, Xuzhen Guo, Jiasong Li, Qi Liu, Fuying Kang in Biophysics Reports (2018)