29 Result(s)

Article

Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1

Tianxin Wang, Wenqin Tang, **aolei Zhu, Zhenyu Lv, Jiayan Chen, Yongze Li… in Cell Research (2024)

Article

Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3

Fahui Li, Linhua Tai, **aoyu Sun, Zhenyu Lv, Wenqin Tang, Tianxin Wang… in Cell Research (2024)

Protocol

Repurposing Photosensitizer Proteins Through Genetic Code Expansion to Facilitate Photo-Biocatalysis

Artificial photoenzymes with noncanonical photo-redox cofactors have paved the way for enzyme rational design and the creation of new-to-nature biocatalysts. Genetically encoded photo-redox cofactors endow pho...

Jiangyun Wang, Yan **a, Xuzhen Guo in Genetically Incorporated Non-Canonical Amino Acids (2023)

Article

Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser

One of the primary objectives in chemistry research is to observe atomic motions during reactions in real time. Although X-ray free-electron lasers (XFELs) have facilitated the capture of reaction intermediate...

**aohong Liu, Pengcheng Liu, Hongjie Li, Zhen Xu, Lu Jia, Yan **a… in Nature Chemistry (2022)

Article

Discovery of Plasma Membrane-Associated RNAs through APEX-seq

In addition to nucleic acids, a variety of other biomolecules have also been found on the plasma membrane. Although researchers have realized that RNA has the ability to bind to membrane vesicles in vitro, lit...

Erzhong Wu, Xuzhen Guo, Xueyi Teng, Rui** Zhang… in Cell Biochemistry and Biophysics (2021)

Chapter and Conference Paper

Intelligent Frequency Selection of the Sky-Wave Radar Based on Numerical Ray Tracing

The sky-wave radar uses the reflection effect of the ionosphere to achieve trans-horizon transmission, so its performance is directly affected by the ionospheric environment. In this paper, the latest ionosphe...

Runze Li, Jiangyun Wang, Guanghong Gong in Proceedings of 2020 Chinese Intelligent Sy… (2021)

Chapter and Conference Paper

Intelligent Wireless Propagation Model with Environmental Adaptability

Reasonable deployment of base stations can provide users with better services due to the development of 5G. During the deployment, wireless propagation models are used to predict signal coverage. Based on Deep...

**aoyu Qu, Jiangyun Wang in Proceedings of 2020 Chinese Intelligent Systems Conference (2021)

Article

Coupling natural systems with synthetic chemistry for light-driven enzymatic biocatalysis

Visible light-driven redox reactions have been widely adopted for the production of chemicals to combat energy shortage and global warming. Key elements of such a reaction system include a photosensitizer, a c...

Dandan Zheng, Ying Zhang, **aohong Liu, Jiangyun Wang in Photosynthesis Research (2020)

Article

A genetically encoded photosensitizer protein facilitates the rational design of a miniature photocatalytic CO₂-reducing enzyme

Photosensitizers, which harness light energy to upgrade weak reductants to strong reductants, are pivotal components of the natural and artificial photosynthesis machineries. However, it has proved difficult t...

**aohong Liu, Fuying Kang, Cheng Hu, Li Wang, Zhen Xu, Dandan Zheng… in Nature Chemistry (2018)

Article

Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase

Cysteine dioxygenase (CDO) plays an essential role in sulfur metabolism by regulating homeostatic levels of cysteine. Human CDO contains a post-translationally generated Cys93–Tyr157 cross-linked cofactor. Her...

Jiasong Li, Wendell P. Griffith, Ian Davis, Inchul Shin… in Nature Chemical Biology (2018)

Article

Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin

Signals from 800 G-protein-coupled receptors (GPCRs) to many SH3 domain-containing proteins (SH3-CPs) regulate important physiological functions. These GPCRs may share a common pathway by signaling to SH3-CPs ...

Fan Yang, Peng **ao, Chang-xiu Qu, Qi Liu, Liu-yang Wang… in Nature Chemical Biology (2018)

Chapter and Conference Paper

Pixel Convolutional Networks for Skeleton-Based Human Action Recognition

Human action recognition is an important field in computer vision. Skeleton-based models of human obtain more attention in related researches because of strong robustness to external interference factors. In ...

Zhichao Chang, Jiangyun Wang, Liang Han in Methods and Applications for Modeling and … (2018)

Article

Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids

Metalloproteins have inspired chemists for many years to synthesize artificial catalysts that mimic native enzymes. As a complementary approach to studying native enzymes or making synthetic models, biosynthet...

Yang Yu, Chang Cui, Jiangyun Wang, Yi Lu in Science China Chemistry (2017)

Chapter and Conference Paper

Research on Synthetic Natural Environment Data Cube Based on XML B+ Tree Structure

Because the synthetic natural environment data has many characteristics of multi-source, heterogeneous and massive, the data cube technology which can handle multi-dimensional data is applied to the synthetic ...

Chao Lin, JiangYun Wang, Liang Han in Modeling, Design and Simulation of Systems (2017)

Chapter and Conference Paper

Trajectory Modeling and Simulation of Anti-missile Interception of Warship Based Missile

Air defense combat is one of the important parts in the research of surface ships. In the long-range missile intercepting maneuvering targets is a key link of warship air defense systems. Especially, in this p...

Yunbo Gao, Liang Han, Jiangyun Wang in Theory, Methodology, Tools and Application… (2016)

Article

Functional tuning and expanding of myoglobin by rational protein design

Rational protein design is a powerful strategy, not only for revealing the structure and function relationship of natural metallo-proteins, but also for creating artificial metalloproteins with improved proper...

YingWu Lin, JiangYun Wang, Yi Lu in Science China Chemistry (2014)