10 Result(s)
within
Wojciech Fendler
Biomedicine
English
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Article
Open AccessMicroRNAs predict early complications of autologous hematopoietic stem cell transplantation
Autologous hematopoietic stem cell transplantation (AHSCT) remains the most prevalent type of stem cell transplantation. In our study, we investigated the changes in circulating miRNAs in AHSCT recipients and ...
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Article
Open AccessBiological basis of extensive pleiotropy between blood traits and cancer risk
The immune system has a central role in preventing carcinogenesis. Alteration of systemic immune cell levels may increase cancer risk. However, the extent to which common genetic variation influences blood tra...
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Article
Open AccessExpression-based decision tree model reveals distinct microRNA expression pattern in pediatric neuronal and mixed neuronal-glial tumors
The understanding of the molecular biology of pediatric neuronal and mixed neuronal-glial brain tumors is still insufficient due to low frequency and heterogeneity of those lesions which comprise several subty...
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Article
Open AccessCirculating miR-29a and miR-150 correlate with delivered dose during thoracic radiation therapy for non-small cell lung cancer
Risk of normal tissue toxicity limits the amount of thoracic radiation therapy (RT) that can be routinely prescribed to treat non-small cell lung cancer (NSCLC). An early biomarker of response to thoracic RT m...
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Article
The Role of CXC Chemokines in Pulmonary Fibrosis of Systemic Lupus Erythematosus Patients
The inflammatory process in systemic lupus erythematosus (SLE) affects many organs including the lungs. CXC chemokines are suggested to play an important role in the pathogenesis of SLE and pulmonary fibrosis....
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Open AccessLipid peroxidation and glutathione peroxidase activity relationship in breast cancer depends on functional polymorphism of GPX1
Since targeting oxidative stress markers has been recently recognized as a novel therapeutic target in cancer, it is interesting to investigate whether genetic susceptibility may modify oxidative stress respon...
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Article
The NR3C1 Glucocorticoid Receptor Gene Polymorphisms May Modulate the TGF-beta mRNA Expression in Asthma Patients
Glucocorticosteroids (GCs) are basic drugs in therapy of a number of diseases, including chronic diseases of the respiratory system. They are the most important anti-inflammatory drugs in the treatment of asth...
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Open AccessAvailability and outcomes of radiotherapy in Central Poland during the 2005-2012 period - an observational study
Using a cross-database integrative approach, we performed an epidemiological analysis in a representative region of central Poland to evaluate the availability of radiotherapy (RTx) and overall survival of adu...
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Article
Open AccessExhaled IL-8 in Systemic Lupus Erythematosus with and without Pulmonary Fibrosis
The purpose of this study is to evaluate the relationship between the concentration of interleukin-8 (IL-8) in exhaled breath condensate (EBC) and bronchoalveolar lavage fluid (BALF) with the disease activity ...
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Article
Open AccessGenetic Polymorphisms and the Risk of Myocardial Infarction in Patients Under 45 Years of Age
This study investigates the potential role of 17 chosen polymorphisms in 15 candidate genes and the risk of myocardial infarction in patients under 45 years of age. The study consists of 271 patients with myoc...
