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  1. Article

    Open Access

    The predictive value of BOAH scale for screening obstructive sleep apnea in patients at a sleep clinic in Scotland

    The study aimed to evaluate the diagnostic value of an original questionnaire for obstructive sleep apnea (OSA), the BOAH scale, and its ability to prioritize patients at high risk for OSA for polysomnography ...

    Agata Gabryelska, Łukasz Mokros, Grzegorz Kardas, Michał Panek… in Sleep and Breathing (2021)

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  2. Article

    Open Access

    Primary non-adherence to inhaled medications measured with e-prescription data from Poland

    Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland,...

    Grzegorz Kardas, Michał Panek, Piotr Kuna… in Clinical and Translational Allergy (2020)

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  3. No Access

    Article

    Identification of Relationships Between Interleukin 15 mRNA and Brain-Derived Neurotrophic Factor II mRNA Levels With Formal Components of Temperament in Asthmatic Patients

    Asthma is a chronic inflammatory and heterogeneous disease develo** mostly through allergic inflammation, which modifies the expression of various cytokines and neurotrophins. Previous studies suggest the in...

    Michał Panek, Mateusz Jonakowski, Jan Zioło, Tadeusz Pietras… in Molecular Neurobiology (2017)

  4. No Access

    Article

    The NR3C1 Glucocorticoid Receptor Gene Polymorphisms May Modulate the TGF-beta mRNA Expression in Asthma Patients

    Glucocorticosteroids (GCs) are basic drugs in therapy of a number of diseases, including chronic diseases of the respiratory system. They are the most important anti-inflammatory drugs in the treatment of asth...

    Michał Panek, Tadeusz Pietras, Artur Fabijan, Jan Zioło, Łukasz Wieteska… in Inflammation (2015)

  5. Article

    Open Access

    The role of functional single nucleotide polymorphisms of the human glucocorticoid receptor gene NR3C1 in Polish patients with bronchial asthma

    N363S and ER22/23EK polymorphisms observed within glucocorticoid receptor gene (NR3C1) may play an important role in the development of bronchial asthma. NR3C1 gene is associated with an altered sensitivity to...

    Michał Panek, Tadeusz Pietras, Adam Antczak, Paweł Górski… in Molecular Biology Reports (2012)

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  6. No Access

    Article

    Functional polymorphism of cyclooxygenase-2 gene (G–765C) in chronic obstructive pulmonary disease patients

    Cyclooxygenase two (COX-2) is an important enzyme metabolizing arachidonic acid. In contrast to constitutive cyclooxygenase one (COX-1), COX-2 is induced by proinflammatory factors. Polymorphism −765G/C in COX...

    Tadeusz Pietras, Janusz Szemraj, Michał Panek, Andrzej Witusik… in Molecular Biology Reports (2012)

  7. Article

    Open Access

    The Bcl I single nucleotide polymorphism of the human glucocorticoid receptor gene h-GR/NR3C1 promoter in patients with bronchial asthma: pilot study

    Bcl I in the promoter polymorphism observed within h-GR/NR3C1 gene may play an important role in the development of bronchial asthma and resistance to GCs in the severe bronchial asthma. The aim of the investigat...

    Tadeusz Pietras, Michał Panek, Damian Tworek… in Molecular Biology Reports (2011)

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