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    Using modern approaches to sedimentation velocity to detect conformational changes in proteins

    It has been known for decades that proteins undergo conformational changes in response to binding ligands. Such changes are usually accompanied by a loss of entropy by the protein, and thus conformational chan...

    Chad A. Brautigam, Shih-Chia Tso, Ranjit K. Deka, Wei Z. Liu… in European Biophysics Journal (2020)