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Article
Open AccessPrenatal fever and autism risk
Some studies suggest that prenatal infection increases risk of autism spectrum disorders (ASDs). This study was undertaken in a prospective cohort in Norway to examine whether we could find evidence to support...
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Article
Open AccessImmune network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome with atypical and classical presentations
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a persistent and debilitating disorder marked by cognitive and sensory dysfunction and unexplained physical fatigue. Classically, cases present af...
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Article
Cytokine network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome
Myalgic encephalomyelitis/chronic fatigue syndrome is an unexplained debilitating disorder that is frequently associated with cognitive and motor dysfunction. We analyzed cerebrospinal fluid from 32 cases, 40 ...
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Article
West Nile Virus in the British Virgin Islands
West Nile virus (WNV) first emerged in the US in 1999 and has since spread across the Americas. Here, we report the continued expansion of WNV to the British Virgin Islands following its emergence in a flock o...
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Article
Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder
In 1983, reports of antibodies in subjects with major depressive disorder (MDD) to an as-yet uncharacterized infectious agent associated with meningoencephalitis in horses and sheep led to molecular cloning of...
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Article
The Autism Birth Cohort: a paradigm for gene–environment–timing research
The reported prevalence of autism spectrum disorders (ASDs) has increased by 5- to 10-fold over the past 20 years. Whether ASDs are truly more frequent is controversial; nonetheless, the burden is profound in ...
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Article
Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection
Streptococcal infections can induce obsessive-compulsive and tic disorders. In children, this syndrome, frequently associated with disturbances in attention, learning and mood, has been designated pediatric au...
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Article
Open AccessExamining Landscape Factors Influencing Relative Distribution of Mosquito Genera and Frequency of Virus Infection
Mosquito-borne infections cause some of the most debilitating human diseases, including yellow fever and malaria, yet we lack an understanding of how disease risk scales with human-driven habitat changes. We p...
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Article
Natural M-segment reassortment in Potosi and Main Drain viruses: implications for the evolution of orthobunyaviruses
Recently, we identified Batai virus as the M-segment reassortment partner of Ngari virus. Extension of genetic analyses to other orthobunyaviruses related to the Bunyamwera serogroup indicates additional natur...
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Article
Neurotoxic effects of postnatal thimerosal are mouse strain dependent
The develo** brain is uniquely susceptible to the neurotoxic hazard posed by mercurials. Host differences in maturation, metabolism, nutrition, sex, and autoimmunity influence outcomes. How population-based ...
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Article
Banbury Center of Cold Spring Harbor meeting on microbiology, immunology and toxicology of autism and other neurodevelopmental disorders February 11–14, 2001
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Article
Infectious and immune factors in neurodevelopmental damage
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Chapter
Borna Disease Virus Infection of Adult and Neonatal Rats: Models for Neuropsychiatric Disease
Borna disease virus (BDV) is a newly classified RNA virus (Briese et al. 1994; Cubitt et al. 1994; Schneemann et al. 1995), worldwide in distribution, that infects the central nervous system (CNS) of warm-blooded...
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Article
Orofacial dyskinesias and dystonia in rats infected with Borna disease virus; a model for tardive dyskinetic syndromes
The neurochemical and lesion effects of Borna disease virus infection in rats result in a syndrome with phenotypic and pharmacological similarities to tardive dyskinesia.
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Article
The search for infectious agents in neuropsychiatric disorders: lessons from multiple sclerosis
Central nervous system diseases, such as multiple sclerosis, may have an infectious basis; however, it has been particularly challenging to identify specific agents.
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Chapter
Behavioral Disturbances and Pharmacology of Borna Disease
Whether Borna disease virus (BDV) or related infectious agents cause human disease remains controversial (see Bode and Amsterdam, this volume). Nonetheless, the Borna disease (BD) system has unique features th...
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Chapter
Molecular Biology of Borna Disease Virus
Originally described in the early nineteenth century as a fatal encephalitis in horses, Borna disease (BD) has become an extraordinarily valuable model for the study of both molecular mechanisms and biological...
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Chapter and Conference Paper
Whole Animal Section In Situ Hybridization and Protein Blotting: New Tools in Molecular Analysis of Animal Models for Human Disease
Laboratory animals continue to be invaluable in the study of the pathogenesis and management of infectious diseases. Development of nucleic acid and antibody technologies have facilitated analysis of animal in...
